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首页> 外文期刊>BMC Gastroenterology >Typical symptoms and not positive reflux-cough correlation predict cure of gastroesophageal reflux disease related chronic cough after laparoscopic fundoplication: a retrospective study
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Typical symptoms and not positive reflux-cough correlation predict cure of gastroesophageal reflux disease related chronic cough after laparoscopic fundoplication: a retrospective study

机译：回顾性研究：典型症状和反流-咳嗽相关性不正可预测胃食管反流病相关慢性咳嗽的治愈

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摘要

The effect of laparoscopic fundoplication on reflux-related chronic cough is unpredictable, the aim of the study is to investigate the predictive effect of positive reflux-cough correlation on the resolution of reflux-related chronic cough after anti-reflux surgery. A 5?years retrospective review was performed. Logistic regression analysis was used to determine the independent predictors on the cure of chronic cough. Seventy-nine patients were included in this study, among which chronic cough was cured in 47 (59.5%) and significantly improved in 10 (12.7%) patients. Present of typical symptoms (odds ratio?=?6.435,95% confidence interval [CI]?=?1.427–29.032, p?=?0.015) and number of Reflux episodes (impedance) ≥73 (odds ratio?=?0.306, 95% confidence interval [CI]?=?0.107–0.874, p?=?0.027) were significantly associated with the cure of chronic cough. laparoscopic fundoplicaiton is effective for the management of reflux-related chronic cough, particularly with the present of typical symptoms.
机译：腹腔镜胃底折叠术对反流相关性慢性咳嗽的影响是无法预测的，本研究的目的是研究正反流性咳嗽相关性对反流手术后反流相关性慢性咳嗽的预测作用。进行了5年的回顾性审查。使用逻辑回归分析确定慢性咳嗽治愈的独立预测因子。这项研究纳入了79名患者，其中慢性咳嗽治愈47例（59.5％），而10例慢性咳嗽（12.7％）明显改善。典型症状的出现（几率=？6.435，95％置信区间[CI]？=？1.427-29.032，p？=？0.015）和反流发作次数（阻抗）≥73（几率？=？0.306， 95％的置信区间[CI]？=？0.107-0.874，p？=？0.027）与慢性咳嗽的治愈显着相关。腹腔镜胃底镜术可有效治疗与回流有关的慢性咳嗽，特别是在出现典型症状时。

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