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首页> 外文期刊>BMC Gastroenterology >Useful condition of chromoendoscopy with indigo carmine and acetic acid for identifying a demarcation line prior to endoscopic submucosal dissection for early gastric cancer
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Useful condition of chromoendoscopy with indigo carmine and acetic acid for identifying a demarcation line prior to endoscopic submucosal dissection for early gastric cancer

机译:靛蓝胭脂红和乙酸在彩色内窥镜检查中用于早期胃癌内镜黏膜下剥离术之前确定分界线的有用条件

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Background Identifying a precise demarcation line (DL) is indispensable for pathological complete en bloc endoscopic submucosal dissection (ESD) for early gastric cancer (EGC). We evaluated the useful condition of chromoendoscopy with indigo carmine and acetic acid for marking dots around lesions before ESD for EGC. Methods We examined 98 consecutive patients with 109 intramucosal EGCs (mean diameter, 17.8?±?12.4?mm; main histologic type, 96 intestinal and 13 diffuse) resected by en bloc ESD after chromoendoscopy with indigo carmine and acetic acid between December 2012 and February 2014. The DL was identified by this technique just before ESD (mean chromoendoscopy observation time, 71.6?s); subsequently, marking dots were placed around the EGC. EGCs were classified into two groups: useful for identifying the DL or useless. Clinicopathological characteristics and clinical outcomes were evaluated in each group. Results Forty-two of the 109 cases (38.5?%) were determined useful for chromoendoscopy with indigo carmine and acetic acid. Multivariate analysis with logistic regression showed that macroscopic type (protruded or flat elevated-type) and atrophic border (the oral side of tumor) were independently associated with the usefulness of chromoendoscopy using indigo carmine and acetic acid for identifying the DL of EGCs ( P Conclusions Before ESD, chromoendoscopy with indigo carmine and acetic acid can be used for creating precise markings in protruded or flat elevated-type EGC or at the atrophic border on the oral side of EGCs.
机译:背景技术对于早期胃癌(EGC)的病理完整整体内镜下粘膜下剥离术(ESD),确定精确的分界线(DL)是必不可少的。我们评估了用靛蓝胭脂红和乙酸进行色内镜检查的有用条件,以便在进行EGC ESD之前在病变周围标记点。方法我们在2012年12月至2月之间,采用靛蓝胭脂红和醋酸色膜内窥镜检查,对98例患者进行了109例粘膜内EGC(平均直径17.8±12.4毫米;主要组织学类型,96例肠道和13例弥漫性)切除,并通过整体ESD切除。 2014年。通过该技术在ESD之前鉴定了DL(平均色内窥镜观察时间为71.6?s)。随后,在EGC周围放置标记点。 EGC分为两类:可用于识别DL或无用。在每组中评估临床病理特征和临床结果。结果109例病例中有42例(38.5%)可用于靛蓝胭脂红和乙酸的色谱内镜检查。逻辑回归的多变量分析表明,宏观类型(突出或扁平升高型)和萎缩性边界(肿瘤的口腔侧)与使用靛蓝胭脂红和乙酸鉴定EGC DL的内窥镜检查的有用性相关(P结论在进行ESD之前,可以使用靛蓝胭脂红和乙酸的色谱内窥镜在突出的或平坦的升高型EGC或EGC口腔侧的萎缩性边界上创建精确的标记。

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