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Self-medication with antibiotics in rural population in Greece: a cross-sectional multicenter study

机译：希腊农村人口自我用药的抗生素：多中心横断面研究

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Background Self-medication is an important driver of antimicrobial overuse as well as a worldwide problem. The aim of the present study was to estimate the use of antibiotics, without medical prescription, in a sample of rural population presenting in primary care in southern Greece. Methods The study included data from 1,139 randomly selected adults (545 men/594 women, mean age ± SD: 56.2 ± 19.8 years), who visited the 6 rural Health Centres of southern Greece, between November 2009 and January 2010. The eligible participants were sought out on a one-to-one basis and asked to answer an anonymous questionnaire. Results Use of antibiotics within the past 12 months was reported by 888 participants (77.9%). 508 individuals (44.6%) reported that they had received antibiotics without medical prescription at least one time. The major source of self-medication was the pharmacy without prescription (76.2%). The antibiotics most frequently used for self-medication were amoxicillin (18.3%), amoxicillin/clavulanic acid (15.4%), cefaclor (9.7%), cefuroxim (7.9%), cefprozil (4.7%) and ciprofloxacin (2.3%). Fever (41.2%), common cold (32.0%) and sore throat (20.6%) were the most frequent indications for the use of self-medicated antibiotics. Conclusion In Greece, despite the open and rapid access to primary care services, it appears that a high proportion of rural adult population use antibiotics without medical prescription preferably for fever and common cold.
机译：背景技术自我药物治疗是抗菌药物过度使用以及全球性问题的重要驱动因素。本研究的目的是评估在希腊南部进行初级保健的农村人口样本中，在没有医疗处方的情况下使用抗生素的情况。方法该研究包括来自2009年11月至2010年1月间访问希腊南部6个农村卫生中心的1139名成年人（545名男性/ 594名女性，平均年龄±SD：56.2±19.8岁）的数据。一对一地寻找答案，并要求回答匿名问卷。结果888名参与者报告了过去12个月内使用抗生素的情况（占77.9％）。 508个人（44.6％）报告说，他们至少有一次没有使用医学处方而接受了抗生素。自我用药的主要来源是没有处方的药房（占76.2％）。最常用于自我用药的抗生素是阿莫西林（18.3％），阿莫西林/克拉维酸（15.4％），头孢克洛（9.7％），头孢呋辛（7.9％），头孢曲唑（4.7％）和环丙沙星（2.3％）。发烧（41.2％），普通感冒（32.0％）和喉咙痛（20.6％）是使用自用抗生素的最常见指征。结论在希腊，尽管开放和快速地获得了初级保健服务，但似乎仍有很大一部分农村成年人使用没有医学处方的抗生素，最好用于发烧和普通感冒。

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