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首页> 外文期刊>BMC Family Practice >Medically unexplained physical symptoms and work functioning over 2?years: their association and the influence of depressive and anxiety disorders and job characteristics
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Medically unexplained physical symptoms and work functioning over 2?years: their association and the influence of depressive and anxiety disorders and job characteristics

机译：超过2年的医学上无法解释的身体症状和工作功能：它们的关联以及抑郁和焦虑症的影响以及工作特征

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Background Medically unexplained physical symptoms (MUPS) are highly prevalent and may affect work functioning. In this study we aimed to assess the longitudinal association between MUPS and work functioning over 2?years and the influence of job characteristics and depressive and anxiety disorders on this association. Methods We assessed the longitudinal association between MUPS and work functioning, operationalized in terms of absenteeism and disability at work, in 1887 working participants from the Netherlands Study of Depression and Anxiety (NESDA). The NESDA study population included participants with a current depressive and/or anxiety disorder, participants with a lifetime risk and/or subthreshold symptoms and healthy controls. Absenteeism was assessed with the Health and Labour Questionnaire Short Form and disability with the World Health Organization Disability Assessment Schedule II. MUPS were measured with the Four Dimensional Symptom Questionnaire. Measurements were taken at baseline and at 2?years follow-up. We used mixed model analyses to correct for the dependency of observations within participants. Results MUPS were positively associated with disability (regression coefficient 0.304; 95?% CI 0.281–0.327) and with short and long-term absenteeism over 2?years (OR 1.030, 95?% CI 1.016–1.045; OR 1.099, 95?% CI 1.085–1.114). After adjusting for depressive disorders, anxiety disorders and job characteristics, associations weakened but remained significant. Conclusion Our results show that MUPS were positively associated with disability and absenteeism over 2?years, even after adjusting for depressive and anxiety disorders and job characteristics. This suggests that early identification of MUPS and adequate management is important.
机译：背景技术医学上无法解释的身体症状（MUPS）非常普遍，可能会影响工作功能。在这项研究中，我们旨在评估MUPS与2年以上工作功能之间的纵向关联，以及工作特征，抑郁和焦虑症对该关联的影响。方法我们评估了MUPS与工作功能之间的纵向关联性，该关联性是根据1887年荷兰抑郁症和焦虑症研究（NESDA）的工作参与者的旷工和残疾情况进行的。 NESDA研究人群包括患有当前抑郁和/或焦虑症的参与者，具有终生风险和/或亚阈值症状的参与者以及健康对照者。缺勤情况通过《卫生和劳工调查问卷简表》进行评估，残障情况通过《世界卫生组织残障评估表II》进行评估。 MUPS用四度症状问卷调查。在基线和随访2年时进行测量。我们使用混合模型分析来纠正参与者中观察的依赖性。结果MUPS与残疾呈正相关（回归系数0.304; 95％CI为0.281-0.327）以及2年以上的长期和长期缺勤（OR 1.030，95％CI 1.016-1.045; OR 1.099，95％ CI 1.085–1.114）。在调整了抑郁症，焦虑症和工作特征后，联想减弱，但仍然很重要。结论我们的结果表明，即使在调整了抑郁症和焦虑症以及工作特征后，MUPS与残疾和旷工在2年内仍呈正相关。这表明对MUPS进行早期识别和适当管理很重要。

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