...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>BMC Urology >Upper urinary tract stone disease in patients with poor performance status: active stone removal or conservative management?
【24h】

Upper urinary tract stone disease in patients with poor performance status: active stone removal or conservative management?

机译：上尿路结石病患者的不良表现状态：积极清除结石还是保守治疗？

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

It remains controversial as to whether active stone removal should be performed in patients with poor performance status because of their short life expectancy and perioperative risks. Our objectives were to evaluate treatment outcomes of active stone removal in patients with poor performance status and to compare life prognosis with those managed conservatively. We retrospectively reviewed 74 patients with Eastern Cooperative Oncology Group performance status 3 or 4 treated for upper urinary tract calculi at our four hospitals between January 2009 and March 2016. Patients were classified into either surgical treatment group or conservative management group based on the presence of active stone removal. Stone-free rate and perioperative complications in surgical treatment group were reviewed. In addition, we compared overall survival and stone-specific survival between the two groups. Cox proportional hazards analysis was performed to investigate predictors of overall survival and stone-specific survival. Fifty-two patients (70.3%) underwent active stone removal (surgical treatment group) by extracorporeal shock wave lithotripsy (n?=?6), ureteroscopy (n?=?39), percutaneous nephrolithotomy (n?=?6) or nephrectomy (n?=?1). The overall stone-free rate was 78.8% and perioperative complication was observed in nine patients (17.3%). Conservative treatment was undergone by 22 patients (29.7%) (conservative management group). Two-year overall survival rates in surgical treatment and conservative management groups were 88.0% and 38.4%, respectively (p?
机译：由于预期寿命短和围手术期风险，在状态不佳的患者中是否应进行主动结石清除仍存在争议。我们的目标是评估表现不佳的患者主动结石的治疗效果，并将其寿命与保守治疗的患者进行比较。我们回顾性回顾了2009年1月至2016年3月间在我们的四家医院接受上泌尿道结石治疗的74例东部合作肿瘤小组表现为3或4的患者。根据患者的活动状态将患者分为手术治疗组或保守治疗组去除石头。回顾手术治疗组的无结石发生率和围手术期并发症。此外，我们比较了两组的总体生存率和结石特异性生存率。进行了Cox比例风险分析，以调查整体生存率和结石特异性生存率的预测因子。 52例（70.3％）患者接受了体外冲击波碎石术（n = 6），输尿管镜检查（n = 39），经皮肾镜取石术（n = 6）或肾切除术，积极切除了结石（外科治疗组）。 （n？=？1）。 9名患者（17.3％）的总无结石率为78.8％，并观察到围手术期并发症。保守治疗22例（29.7％）（保守治疗组）。手术治疗组和保守治疗组的两年总生存率分别为88.0％和38.4％（p <0.01），两组的两年结石特异性生存率分别为100.0％和61.3％（ p≤0.01。在多变量分析中，结石清除率不显着，但被认为可能是总体存活率的有利预测指标（p = 0.07）。此外，结石清除是结石特异性生存的唯一独立预测因子（p <0.01）。对于表现差的患者，积极安全地清除结石可以安全有效地进行。与保守治疗相比，手术结石治疗可获得更长的总生存期和特定结石生存期。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号