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首页> 外文期刊>BMJ Open Respiratory Research >An observational study of PM10 and hospital admissions for acute exacerbations of chronic respiratory disease in Tasmania, Australia 1992–2002
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An observational study of PM10 and hospital admissions for acute exacerbations of chronic respiratory disease in Tasmania, Australia 1992–2002

机译：1992-2002年，塔斯马尼亚州，PM10和医院入院的慢性呼吸道疾病急性发作的观察性研究

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Objective Particulate matter with a diameter below 10?μ (PM10) has been a major concern in the Tamar Valley, Launceston, where wood heaters are extensively used. We examined the relationship between PM10 levels, meteorological variables, respiratory medications and hospital admissions for respiratory disease over the decade 1992–2002. Methods PM10 levels were provided by the Department of Primary Industry Water, Parks and Environment, and meteorological variables from the Bureau of Meteorology. We obtained hospital discharge codes for the Launceston General Hospital. Poisson regression was used for statistical analyses. Results Mean daily PM10 levels declined from 50.7 to 16.5?μg/m3. Hospitalisations for asthma decreased from 29 to 21 per month, whereas chronic obstructive pulmonary disease (COPD) increased and bronchitis/bronchiolitis remained unchanged. We found a 10?μg/m3 increase in PM10 to be associated with a 4% increase in admissions for acute bronchitis/bronchiolitis (p0.05), but no association with asthma or COPD was found. All respiratory diseases showed seasonal patterns of hospitalisation. Conclusions This is the first long-term study in Australia to demonstrate an association between PM10 levels and respiratory diseases. Reducing exposure to PM10 may decrease hospital admissions for respiratory diseases. Implication Better preventive measures, including sustained public health initiatives to combat air pollution, are required to reduce respiratory morbidity.
机译：目标直径低于10？μ（PM 10 ）的颗粒物已成为朗塞斯顿塔玛谷（Tamar Valley）的主要问题，那里广泛使用木材加热器。我们研究了1992-2002十年间PM 10 水平，气象变量，呼吸道药物和呼吸道疾病住院之间的关系。方法由主要产业水，公园和环境部提供PM 10 水平，并由气象局提供气象变量。我们获得了朗塞斯顿综合医院的出院代码。使用泊松回归进行统计分析。结果每日平均PM 10 水平从50.7降至16.5？g / m 3 。哮喘的住院治疗从每月29例减少至21例，而慢性阻塞性肺疾病（COPD）有所增加，支气管炎/细支气管炎保持不变。我们发现PM 10 升高10？μg/ m 3 与急性支气管炎/细支气管炎的住院率增加4％（p0.05）有关，但没有发现与哮喘或COPD相关。所有呼吸系统疾病均显示住院的季节性模式。结论这是澳大利亚首项长期研究，证明PM 10 水平与呼吸系统疾病之间存在关联。减少暴露于PM 10 可能会减少呼吸道疾病的住院人数。含义需要采取更好的预防措施，包括采取持续的公共卫生措施来应对空气污染，以减少呼吸道疾病。

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