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首页> 外文期刊>BMJ Open Respiratory Research >Self-reported symptoms of chronic cough and breathlessness in working-age men in the city of Izhevsk, Russia: associations with cardiovascular disease risk factors and comorbidities
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Self-reported symptoms of chronic cough and breathlessness in working-age men in the city of Izhevsk, Russia: associations with cardiovascular disease risk factors and comorbidities

机译：俄罗斯伊热夫斯克市劳动年龄人群自我报告的慢性咳嗽和呼吸困难症状：与心血管疾病危险因素和合并症的关系

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Introduction Very little is known about the prevalence of respiratory symptoms or their associations with other health conditions in Russia. Methods Between 2008 and 2010, a sample of 983 men resident in Izhevsk, Russia, took part in a cross-sectional survey. Presence of respiratory symptoms was determined from self-report of chronic productive cough and breathlessness assessed using the British Medical Research Council (MRC) breathlessness scale. Self-reported physical and mental health were measured using the 12-Item Short-Form Health Survey (SF-12). Hypertension was assessed from mean blood pressure measured at the health check and/or self-reported use of antihypertensive medication. Other comorbidities were assessed from self-report. Logistic regression models were fitted assessing the association between respiratory symptoms and comorbidities. Linear regression models were fitted to investigate the association between respiratory symptoms and self-reported health scores. All models were adjusted for age, education and smoking status. Results The age-standardised prevalence of cough and breathlessness was 20.9% (prevalence with breathlessness MRC grade 3 or above 3.7%). The majority of men with respiratory symptoms (87.3%) were current smokers. Cough and breathlessness were associated with substantially worse self-reported physical and mental health (test for trend with severity of breathlessness p0.001). Those with chronic cough and grade 3 or above breathlessness had higher odds of having hypertension (OR 3.03; 95% CI 1.36 to 6.74), diabetes (OR 10.55; 95% CI 2.69 to 41.37), angina pectoris (OR 7.54; 95% CI 3.61 to 15.73), previous myocardial infarction (OR 7.61; 95% CI 2.10 to 27.4) and previous stroke (OR 6.61; 95% CI 1.75 to 23.34) compared with those without respiratory symptoms. Conclusions The prevalence of respiratory symptoms was high. Strong associations were found between respiratory symptoms and cardiovascular comorbidities. These are of particular importance given the extremely high level of cardiovascular disease mortality in Russia.
机译：简介在俄罗斯，人们对呼吸道症状的流行或其与其他健康状况的关联了解甚少。方法在2008年至2010年之间，对居住在俄罗斯伊热夫斯克的983名男性进行了抽样调查。呼吸道症状的存在是通过使用英国医学研究理事会（MRC）呼吸困难量表评估的慢性生产性咳嗽和呼吸困难的自我报告确定的。使用12项简短健康调查（SF-12）测量自我报告的身心健康。根据健康检查和/或自行报告的降压药物使用中测得的平均血压评估高血压。通过自我报告评估其他合并症。使用Logistic回归模型评估呼吸道症状与合并症之间的关联。拟合线性回归模型以研究呼吸道症状与自我报告的健康评分之间的关​​联。所有模型都针对年龄，教育程度和吸烟状况进行了调整。结果年龄标准化咳嗽和呼吸困难的患病率为20.9％（MRC 3级或以上的呼吸困难患病率为3.7％）。大多数有呼吸道症状的男性（87.3％）是目前吸烟者。咳嗽和呼吸困难与自我报告的身体和精神健康状况严重恶化有关（测试呼吸困难严重程度的趋势，p <0.001）。患有慢性咳嗽且3级或以上呼吸困难的患者发生高血压的几率更高（OR 3.03; 95％CI 1.36至6.74），糖尿病（OR 10.55; 95％CI 2.69至41.37），心绞痛（OR 7.54; 95％CI与没有呼吸道症状的患者相比，之前的心肌梗死（OR 7.61; 95％CI 2.10至27.4）和先前的中风（OR 6.61; 95％CI 1.75至23.34）。结论呼吸系统症状的患病率较高。在呼吸系统症状和心血管合并症之间发现强烈的关联。考虑到俄罗斯极高的心血管疾病死亡率，这些特别重要。

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