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A case of giant panda ovarian cancer diagnosis and histopathology

机译：大熊猫卵巢癌一例诊断与组织病理学

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Ovarian cancer is diagnosed clinically by detecting ovarian cancer-related factors and markers. Here, we report a case of giant panda ovarian tumor metastasis with a combination of clinical and histopathological diagnosis. Histopathological studies revealed severe lesions and tumor cells in the ovaries, lungs, spleen, kidneys and perianal tissue. Immunohistochemistry staining showed that the ovarian cancer markers B7-H4, CA125, and HE4 were highly expressed in the lungs, kidneys, spleen, ovaries and perianal tissue. Tumor marker tests detected significantly high levels of AFP in serum. Clinical biomarkers combined with histopathology can provide a more accurate diagnosis of ovarian cancer metastasis and identification of ovarian cancer types than either method alone. The giant panda’s death may be due to granulosa cell tumor and theca cell tumor metastasis causing multiple organ dysfunction or even failure.
机译：通过检测卵巢癌相关因子和标记物可在临床上诊断出卵巢癌。在这里，我们报告一例大熊猫卵巢肿瘤转移，结合临床和组织病理学诊断。组织病理学研究显示卵巢，肺，脾，肾和肛周组织中有严重的病变和肿瘤细胞。免疫组织化学染色显示，卵巢癌标志物B7-H4，CA125和HE4在肺，肾，脾，卵巢和肛周组织中高表达。肿瘤标记物检测在血清中检测到显着高水平的AFP。与单独的任何一种方法相比，临床生物标记物结合组织病理学可以提供更准确的卵巢癌转移诊断和卵巢癌类型识别。大熊猫之死可能是由于颗粒细胞瘤和theca细胞瘤转移引起多器官功能障碍甚至衰竭。

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