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首页> 外文期刊>BMC Surgery >Cost-effectiveness of laser Doppler imaging in burn care in the Netherlands
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Cost-effectiveness of laser Doppler imaging in burn care in the Netherlands

机译：激光多普勒成像在荷兰烧伤护理中的成本效益

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Background Early accurate assessment of burn depth is important to determine the optimal treatment of burns. The method most used to determine burn depth is clinical assessment, which is the least expensive, but not the most accurate. Laser Doppler imaging (LDI) is a technique with which a more accurate (>95%) estimate of burn depth can be made by measuring the dermal perfusion. The actual effect on therapeutic decisions, clinical outcomes and the costs of the introduction of this device, however, are unknown. Before we decide to implement LDI in Dutch burn care, a study on the effectiveness and cost-effectiveness of LDI is necessary. Methods/design A multicenter randomised controlled trial will be conducted in the Dutch burn centres: Beverwijk, Groningen and Rotterdam. All patients treated as outpatient or admitted to a burn centre within 5 days post burn, with burns of indeterminate depth (burns not obviously superficial or full thickness) and a total body surface area burned of ≤ 20% are eligible. A total of 200 patients will be included. Burn depth will be diagnosed by both clinical assessment and laser Doppler imaging between 2–5 days post burn in all patients. Subsequently, patients are randomly divided in two groups: ‘new diagnostic strategy’ versus ‘current diagnostic strategy’. The results of the LDI-scan will only be provided to the treating clinician in the ‘new diagnostic strategy’ group. The main endpoint is the effect of LDI on wound healing time. In addition we measure: a) the effect of LDI on other patient outcomes (quality of life, scar quality), b) the effect of LDI on diagnostic and therapeutic decisions, and c) the effect of LDI on total (medical and non-medical) costs and cost-effectiveness. Discussion This trial will contribute to our current knowledge on the use of LDI in burn care and will provide evidence on its cost-effectiveness. Trial registration NCT01489540
机译：背景技术早期准确评估烧伤深度对于确定烧伤的最佳治疗方法很重要。确定烧伤深度最常用的方法是临床评估，这是最便宜的方法，但不是最准确的方法。激光多普勒成像（LDI）是一项技术，通过测量皮肤灌注量，可以更准确（> 95％）估算烧伤深度。然而，对治疗决策，临床结果和引入该设备的成本的实际影响尚不清楚。在我们决定在荷兰的烧伤护理中实施LDI之前，有必要对LDI的有效性和成本效益进行研究。方法/设计将在荷兰的Beverwijk，Groningen和Rotterdam烧伤中心进行多中心随机对照试验。所有患者在烧伤后5天内被视为门诊患者或入院到烧伤中心，深度烧伤深度不确定（烧伤表面不明显或表面不全），且总烧伤表面积不超过20％。总共将包括200名患者。所有患者在烧伤后2至5天之间，将通过临床评估和激光多普勒成像诊断烧伤深度。随后，将患者随机分为两组：“新诊断策略”与“当前诊断策略”。 LDI扫描的结果只会提供给“新诊断策略”组中的主治医生。主要终点是LDI对伤口愈合时间的影响。此外，我们还测量：a）LDI对其他患者预后的影响（生活质量，疤痕质量），b）LDI对诊断和治疗决策的影响，以及c）LDI对总体（医疗和非医疗）影响医疗）成本和成本效益。讨论该试验将有助于我们了解LDI在烧伤护理中的最新应用，并为LDI的成本效益提供证据。试用注册NCT01489540

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