...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>BMC Pulmonary Medicine >Efficacy of a multifactorial intervention on therapeutic adherence in patients with chronic obstructive pulmonary disease (COPD): a randomized controlled trial
【24h】

Efficacy of a multifactorial intervention on therapeutic adherence in patients with chronic obstructive pulmonary disease (COPD): a randomized controlled trial

机译：多因素干预对慢性阻塞性肺疾病（COPD）患者治疗依从性的有效性：一项随机对照试验

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Background Therapeutic adherence of patients with chronic obstructive pulmonary disease (COPD) is poor. This study evaluated the effectiveness of a multifactorial intervention on improving the therapeutic adherence in chronic obstructive pulmonary disease (COPD) patients with scheduled inhalation therapy. Methods The study design consisted of a randomised controlled trial in a primary care setting. 146 patients diagnosed with COPD were randomly allocated into two groups using the block randomisation technique. One-year follow-ups with three visits were performed. The intervention consisted of motivational aspects related to adherence (beliefs and behaviour) in the form of group and individual interviews, cognitive aspects in the form of information about the illness and skills in the form of training in inhalation techniques. Cognitive-emotional aspects and training in inhalation techniques were reinforced during all visits of the intervention group. The main outcome measure was adherence to the medication regimen. Therapeutic adherence was determined by the percentage of patients classified as good adherent as evaluated by dose or pill count. Results Of the 146 participants (mean age 69.8?years, 91.8% males), 41.1% reported adherence (41.9% of the control group and 40.3% of the intervention group). When multifactorial intervention was applied, the reported adherence was 32.4% for the control group and 48.6% for the intervention group, which showed a statistically significant difference (p?=?0.046). Number needed to treat is 6.37. In the intervention group, cognitive aspects increased by 23.7% and skilled performance of inhalation techniques increased by 66.4%. The factors related to adherence when multifactorial intervention was applied were the number of exacerbations (OR?=?0.66), visits to health centre (OR?=?0.93) and devices (OR?=?2.4); illness severity (OR?=?0.67), beta-2-adrenergic (OR?=?0.16) and xantine (OR?=?0.19) treatment; activity (OR?=?1.03) and impact (OR?=?1.03) scales of the Saint George Respiratory Questionnaire. Conclusion Application of the multifactorial intervention designed for this study (COPD information, dose reminders, audio-visual material, motivational aspects and training in inhalation techniques) resulted in an improvement in therapeutic adherence in COPD patients with scheduled inhalation therapy. Trial registration Current Controlled Trials ISRCTN18841601 .
机译：背景慢性阻塞性肺疾病（COPD）患者的治疗依从性差。这项研究评估了采用定期吸入疗法改善慢性阻塞性肺疾病（COPD）患者治疗依从性的多因素干预措施的有效性。方法该研究设计由在初级保健机构中进行的随机对照试验组成。 146名被诊断为COPD的患者使用分组随机技术随机分为两组。进行了一年随访，共进行了3次随访。干预包括以小组和个人访谈的形式与依从性（信念和行为）相关的动机方面，以疾病信息的形式认知方面的认知方面和以吸入技术培训的形式方面的技能。在干预组的所有访问期间，认知情绪方面和吸入技术方面的培训得到了加强。主要结局指标是坚持用药方案。通过依剂量或药丸计数评估为良好依从性的患者百分比确定治疗依从性。结果在146名参与者（平均年龄69.8岁，男性91.8％）中，有41.1％的患者报告了依从性（对照组为41.9％，干预组为40.3％）。当采用多因素干预时，对照组的报告依从性为32.4％，干预组为48.6％，差异有统计学意义（p = 0.046）。需要治疗的数量为6.37。在干预组中，认知方面增加了23.7％，吸入技术的熟练表现增加了66.4％。采用多因素干预时与依从性相关的因素有加重次数（OR≥0.66），就诊中心的访视（OR≥0.93）和器械使用次数（OR≥2.4）。疾病严重程度（OR≥0.67），β-2-肾上腺素（OR≥0.16）和黄嘌呤（OR≥0.19）治疗;活动（OR？=？1.03）和影响（OR？=？1.03）量表。结论为这项研究设计的多因素干预措施（COPD信息，剂量提醒，视听材料，动机方面和吸入技术培训）的应用导致计划吸入治疗对COPD患者的治疗依从性得到改善。试用注册电流控制试验ISRCTN18841601。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号