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首页> 外文期刊>Biotropia: the Southeast Asian journal of tropical biology >ANTIBREAST CANCER ACTIVITY OF NANOPROPOLIS INDONESIA ON INDUCED MAMMARY GLAND TUMOR BY DMBA IN VIRGIN SPRAGUE-DAWLEY RATS
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ANTIBREAST CANCER ACTIVITY OF NANOPROPOLIS INDONESIA ON INDUCED MAMMARY GLAND TUMOR BY DMBA IN VIRGIN SPRAGUE-DAWLEY RATS

机译：DMBA在维珍斯普拉格-道利大鼠体内诱导的纳米胶印度尼西亚对乳腺肿瘤的抗癌活性

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The objective of this study was to determine the effect of nanopropolis to cure cancer induced on rat mammary tumor using 7,12-dimethylbenz(a)anthracene (DMBA). After the first tumors appearance, twenty eight rats were divided into seven groups. Group 1, 2 and 3 served as recipient of nanopropolis dosages 8, 32 and 56 μg/mL treatments; Group 4 served asrecipient of propolis dosage of 233 μg/mL treatment; Group 5 served asrecipient of doxorubicin treatment; Group 6 served as recipient of DMBA treatment and Group 7 as normal group (control). The effect of nanopropolis dosage of 32 μg/mL and propolis dosage of 233 μg/mL were similar in reducing tumor size, healing the wounds caused by the tumor and eliminating cancer cells. It turns out that there is a relationship between particle size absorbent materials. The study suggested that nanopropolis with small concentration was very effective to treatrat mammary gland tumors and breast cancers.Keywords: breast cancer, nanopropolis, propolis, Sprague-Dawley rat
机译：这项研究的目的是确定纳米蜂胶使用7,12-二甲基苯并（a）蒽（DMBA）治愈大鼠乳腺肿瘤所致癌症的效果。在首次出现肿瘤后，将28只大鼠分为7组。第1、2和3组作为纳米蜂胶剂量8、32和56μg/ mL处理的接受者;第4组为蜂胶剂量233μg/ mL的接受者;第5组为阿霉素治疗的接受者;第6组为DMBA治疗的接受者，第7组为正常组（对照组）。纳米蜂胶剂量为32μg/ mL和蜂胶剂量为233μg/ mL的效果在减小肿瘤大小，治愈由肿瘤引起的伤口和消除癌细胞方面相似。事实证明，粒度吸收材料之间存在关系。研究表明低浓度的纳米蜂胶对治疗大鼠乳腺肿瘤和乳腺癌非常有效。关键词：乳腺癌，纳米蜂胶，蜂胶，Sprague-Dawley大鼠

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