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首页> 外文期刊>Brazilian Journal of Infectious Diseases >CD4+ cell counts in patients with different clinical manifestations of tuberculosis
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CD4+ cell counts in patients with different clinical manifestations of tuberculosis

机译：不同临床表现的结核病患者的CD4 +细胞计数

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摘要

Tuberculosis is the prototype of infections that require a cellular immune response for their control. It has been shown that CD4+ T-lymphocytes are most important in the protective response against Mycobacterium tuberculosis. CD8+ T-lymphocytes are also important for effective T-cell immune response. This study compares CD4+ and CD8+ baseline values in patients with different manifestations of tuberculosis. CD4+ and CD8+ in three groups of patients with tuberculosis (pulmonary, lymphadenitis, meningitis/milliary involvement) and a group of healthy volunteers were enumerated using flowcytometry. Twenty-six patients with pulmonary tuberculosis, 10 with adenitis, 16 with meningitis or milliary tuberculosis and 16 healthy volunteers entered the study. Mean CD4 in meningitis/milliary group was significantly lower than all other groups (p
机译：结核病是感染的原型，需要细胞免疫反应来控制。已经表明，CD4 + T淋巴细胞在针对结核分枝杆菌的保护反应中最重要。 CD8 + T淋巴细胞对于有效的T细胞免疫反应也很重要。这项研究比较了患有不同结核病表现的患者的CD4 +和CD8 +基线值。使用流式细胞仪计数了三组结核病患者（肺，淋巴结炎，脑膜炎/微生物受累）和一组健康志愿者中的CD4 +和CD8 +。 26例肺结核患者，10例腺炎，16例脑膜炎或粟粒性肺结核和16名健康志愿者参加了研究。脑膜炎/粟米组的平均CD4明显低于所有其他组（p

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