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首页> 外文期刊>Botanics: Targets and Therapy >Bioactive ingredients of rose hips ( Rosa canina L) with special reference to antioxidative and anti-inflammatory properties: in vitro studies
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Bioactive ingredients of rose hips ( Rosa canina L) with special reference to antioxidative and anti-inflammatory properties: in vitro studies

机译：玫瑰果（Rosa canina L）的生物活性成分，特别涉及抗氧化和抗炎特性：体外研究

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Rosa canina pseudo fruits, often referred to as rose hips, have been used as herbal medicine for more than 2,000 years, yet research has only recently begun to clarify specific mechanisms by which this plant product affects human health. Numerous compounds have been identified, and speculations of their bioactivity have implicated flavonoids, carotenoids, and fatty acids (FAs). With more than 4,500 representatives, flavonoids have been subjected to comprehensive research, with results that suggest various individual structures may be health-promoting compounds, also in rose hips. The importance of carotenoids from R. canina is currently being debated, because the demonstration of specific bioactivity among this group is presently less clear. The benefits of specific FAs have been investigated for decades, and several types of FAs are termed “essential” for human health. The specific mechanisms for bioactivity associated with three FAs that are abundant in R. canina fruits have been clarified in research. For example, linoleic acid, α-linolenic acid (mostly present in the seeds from R. canina ) and a galactolipid ((2S)-1,2-di-O-[(9Z,12Z,15Z)-octadeca-9-12-15-trienoyl]-3-O-β-d-galactopyranosyl glycerol), referred to as GOPO, have been shown to have anti-inflammatory properties. The aim of this review is to critically analyze the published literature on rose hip research, with emphasis on the broadness and varying significance of the publications. Initially, we describe the chemical ingredients of R. canina pseudo fruits, with some focus on what ingredients are found in the whole pseudo fruit and what we know is confined to the seeds (achene seeds), and/or the shells (hypanthium). Then, we evaluate important papers describing the in vitro investigations of the bioactivity and impacts of the constituents of rose hip.
机译：Rosa canina假果，通常被称为玫瑰果，已被用作草药已有2000多年的历史，但直到最近才开始进行研究，以阐明这种植物产品影响人类健康的具体机制。已经鉴定出许多化合物，并且推测其生物活性涉及类黄酮，类胡萝卜素和脂肪酸（FAs）。类黄酮有4,500多个代表，已经进行了全面的研究，结果表明，玫瑰果中的各种单个结构可能是促进健康的化合物。目前正在讨论来自R. canina的类胡萝卜素的重要性，因为目前尚不清楚该人群中特定生物活性的证明。数十年来，已经研究了特定脂肪酸的益处，几种类型的脂肪酸被称为对人类健康至关重要。在研究中已经阐明了与加拿大猕猴桃中丰富的三个FA相关的生物活性的具体机制。例如，亚油酸，α-亚麻酸（主要存在于加拿大茄子的种子中）和半乳糖脂（（2S）-1,2-di-O-[（9Z，12Z，15Z）-octadeca-9-已经显示出称为GOPO的12-15-三烯酰基]-3-O-β-d-吡喃半乳糖基甘油具有抗炎特性。这篇综述的目的是对玫瑰果研究的已发表文献进行批判性分析，重点是出版物的广泛性和不同意义。最初，我们描述了加拿大假单胞菌假果的化学成分，着重于在整个假果中发现了哪些成分，以及我们所知道的局限于种子（ach种子）和/或壳（hy）中。然后，我们评估了重要的论文，这些论文描述了玫瑰果成分的生物活性和影响的体外研究。

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