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Associations between circulating adiponectin and selected plasma biochemical variables in physically active young men and women

机译:身体活跃的青年男女中循环脂联素与血浆生化指标的相关性

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Study aim: To evaluate the relationships between circulating adiponectin and FFA, and other biochemical variables (glycerol, glucose and insulin) in young, healthy non-obese men and women.Material and methods: A group of 53 male and 54 female students participated in the study. The following compounds were determined in plasma: free fatty acids (FFA), glucose and glycerol (colorimetrically), and insulin and adiponectin (by immunoassay). Insulin resistance index (HOMA-IR) was calculated from fasting insulin and glucose concentrations.Results: Mean plasma glucose was slightly lower (p<0.01), and plasma insulin and HOMA-IR markedly higher (p<0.01 - 0.001) in female than in male subjects. Percent body fat was positively correlated with plasma FFA in both groups (p<0.01), but with plasma glycerol (p<0.001) in female students only. Plasma adiponectin was negatively correlated with percent body fat (p<0.02), plasma glycerol (p<0.001) and FFA (p<0.05) in female subjects only.Conclusions: Gender-related differences in body fat may affect the relationship between adiponectin and indices of lipid metabolism.
机译:研究目的:评价年轻健康的非肥胖男性和女性中循环脂联素和FFA与其他生化变量(甘油,葡萄糖和胰岛素)之间的关系。材料与方法:一组53名男生和54名女学生参加研究。在血浆中测定了以下化合物:游离脂肪酸(FFA),葡萄糖和甘油(比色法)以及胰岛素和脂联素(通过免疫测定)。从空腹胰岛素和葡萄糖浓度计算出胰岛素抵抗指数(HOMA-IR),结果表明:女性平均血浆葡萄糖略低(p <0.01),女性血浆胰岛素和HOMA-IR明显较高(p <0.01-0.001)在男性受试者中。两组中的体脂百分比与血浆FFA呈正相关(p <0.01),但仅女学生与血浆甘油(p <0.001)相关。血浆脂联素仅与女性受试者的体脂百分比(p <0.02),血浆甘油(p <0.001)和FFA(p <0.05)呈负相关。结论:性别相关的体内脂肪差异可能会影响脂联素与脂肪的关系。脂质代谢指标。

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