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首页> 外文期刊>Biomedical human kinetics >Physical activity as a protective factor against development of liver steatosis in patients infected with hepatitis C
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Physical activity as a protective factor against development of liver steatosis in patients infected with hepatitis C

机译：体力活动是预防丙型肝炎患者肝脂肪变性发展的保护因素

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Study aim: Was to verify whether the regular practice of physical activity promotes some protective factor against the development of LS in patients infected with hepatitis C virus (HCV). Materials and method: Clinical data were obtained through medical records available at the Pernambuco Liver Institute. Physical activity levels were obtained through the International Physical Activity Questionnaire (IPAQ) short form to classify the patients according to the guidelines of the American College of Sports Medicine (ACSM). Results: The sample consisted of patients of both genders, over 18 years of age, who had positive anti-HCV, HCV-RNA and confirmatory tests for presence or absence of liver steatosis. 126 patients were included in the study. Patients with liver steatosis (G1) were more frequently male (57%) compared to patients without liver steatosis (G2) (p = 0.02). Physical activity analysis showed significant differences for GGT (p = 0.04), HDL (p = 0.04), AF (p = 0.02), viral genotype 3 (p = 0.04) and waist-to-hip ratio (p = 0.01) in anthropometric data. Correlation analysis showed a significant difference for GGT (r = -0.23; p = 0.01) and total bilirubin (BT) (r = -0.22; p = 0.01). Conclusions: Regular practice of physical activity generates a protective factor against the development of LS in patients infected by the hepatitis C virus and it is associated with the maintenance of variables related to hepatic and biochemical damage in patients infected with HCV.
机译：研究目的：验证日常体育锻炼是否能促进丙型肝炎病毒（HCV）感染患者LS的发展。材料和方法：临床数据通过伯南布哥肝病研究所获得的医疗记录获得。通过国际体育活动问卷（IPAQ）简短形式获得体育活动水平，以根据美国运动医学学院（ACSM）的指南对患者进行分类。结果：该样本由18岁以上的男女患者组成，这些患者的抗HCV，HCV-RNA阳性，并证实是否存在肝脂肪变性。 126名患者被纳入研究。与无肝脂肪变性（G2）的患者相比，患有肝脂肪变性（G1）的患者更常见于男性（57％）（p = 0.02）。身体活动分析显示，人体测量的GGT（p = 0.04），HDL（p = 0.04），AF（p = 0.02），病毒基因型3（p = 0.04）和腰臀比（p = 0.01）有显着差异。数据。相关分析显示，GGT（r = -0.23; p = 0.01）和总胆红素（BT）（r = -0.22; p = 0.01）有显着差异。结论：经常进行体育锻炼可以预防丙型肝炎病毒感染患者LS的发展，并且与维持HCV感染患者肝脏和生化损伤相关的变量有关。

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