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首页> 外文期刊>BMC Nephrology >The impact of a multidisciplinary self-care management program on quality of life, self-care, adherence to anti-hypertensive therapy, glycemic control, and renal function in diabetic kidney disease: A Cross-over Study Protocol
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The impact of a multidisciplinary self-care management program on quality of life, self-care, adherence to anti-hypertensive therapy, glycemic control, and renal function in diabetic kidney disease: A Cross-over Study Protocol

机译：多学科自我保健管理计划对糖尿病肾脏疾病的生活质量，自我保健，坚持抗高血压治疗，血糖控制和肾功能的影响：一项交叉研究方案

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Background Diabetic kidney disease, a global health issue, remains associated with high morbidity and mortality. Previous research has shown that multidisciplinary management of chronic disease can improve patient outcomes. The effect of multidisciplinary self-care management on quality of life and renal function of patients with diabetic kidney disease has not yet been well established. Method/Design The aim of this study is to evaluate the impact of a multidisciplinary self-care management program on quality of life, self-care behavior, adherence to anti-hypertensive treatment, glycemic control, and renal function of adults with diabetic kidney disease. A uniform balanced cross-over design is used, with the objective to recruit 40 adult participants with diabetic kidney disease, from public and private out-patient settings in French speaking Switzerland. Participants are randomized in equal number into four study arms. Each participant receives usual care alternating with the multidisciplinary self- care management program. Each treatment period lasts three months and is repeated twice at different time intervals over 12?months depending on the cross-over arm. The multidisciplinary self-care management program is led by an advanced practice nurse and adds nursing and dietary consultations and follow-ups, to the habitual management provided by the general practitioner, the nephrologist and the diabetologist. Data is collected every three months for 12?months. Quality of life is measured using the Audit of Diabetes-Dependent Quality of Life scale, patient self-care behavior is assessed using the Revised Summary of Diabetes Self-Care Activities, and adherence to anti-hypertensive therapy is evaluated using the Medication Events Monitoring System. Blood glucose control is measured by the glycated hemoglobin levels and renal function by serum creatinine, estimated glomerular filtration rate and urinary albumin/creatinine ratio. Data will be analyzed using STATA version 14. Discussion The cross-over design will elucidate the responses of individual participant to each treatment, and will allow us to better evaluate the use of such a design in clinical settings and behavioral studies. This study also explores the impact of a theory-based nursing practice and its implementation into a multidisciplinary context. Trial registration ClinicalTrials.gov identifier: NCT01967901 , registered on the 18th of October 2013.
机译：背景技术糖尿病肾病是全球性的健康问题，仍然与高发病率和高死亡率有关。先前的研究表明，慢性病的多学科管理可以改善患者的预后。跨学科自我护理管理对糖尿病肾病患者生活质量和肾功能的影响尚未得到很好的确立。方法/设计这项研究的目的是评估多学科自我护理管理计划对糖尿病肾病患者的生活质量，自我护理行为，坚持抗高血压治疗，血糖控制和肾功能的影响。 。采用统一的平衡分频设计，目的是从讲法语的瑞士的公共和私人门诊招募40名患有糖尿病肾病的成年参与者。参与者被随机分为四个研究小组。每个参与者都可以在多学科自我护理管理计划的基础上交替接受常规护理。每个治疗期持续三个月，并根据跨接臂的不同，在12个月内以不同的时间间隔重复两次。多学科自我护理管理计划由一名高级执业护士领导，并在全科医生，肾脏科医生和糖尿病专家的惯常管理中增加了护理和饮食咨询以及后续措施。每三个月收集一次数据，持续12个月。使用“糖尿病相关生活质量审核”量表评估生活质量，使用“糖尿病自我护理活动修订摘要”评估患者的自我护理行为，并使用“药物事件监测”系统评估抗高血压治疗的依从性。血糖控制通过糖化血红蛋白水平和肾功能通过血清肌酐，估计的肾小球滤过率和尿白蛋白/肌酐比值来测量。数据将使用STATA版本14进行分析。讨论交叉设计将阐明个体参与者对每种治疗的反应，并使我们能够更好地评估这种设计在临床环境和行为研究中的使用。本研究还探讨了基于理论的护理实践的影响及其在多学科环境中的实施。试验注册ClinicalTrials.gov标识符：NCT01967901，于2013年10月18日注册。

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