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Bilateral somatosensory evoked potentials following intermittent theta-burst repetitive transcranial magnetic stimulation

机译:间歇性theta-burst重复经颅磁刺激后的双边体感诱发电位

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Background Intermittent theta-burst stimulation (iTBS) is a form of repetitive transcranial magnetic stimulation that may alter cortical excitability in the primary somatosensory cortex (SI). The present study investigated the effects of iTBS on subcortical and early cortical somatosensory evoked potentials (SEPs) recorded over left, iTBS stimulated SI and the right-hemisphere non-stimulated SI. SEPs were recorded before and at 5, 15, and 25 minutes following iTBS. Results Compared to pre-iTBS, the amplitude of cortical potential N20/P25 was significantly increased for 5 minutes from non-stimulated SI and for 15 to 25 minutes from stimulated SI. Subcortical potentials recorded bilaterally remained unaltered following iTBS. Conclusion We conclude that iTBS increases the cortical excitability of SI bilaterally and does not alter thalamocortical afferent input to SI. ITBS may provide one avenue to induce cortical plasticity in the somatosensory cortex.
机译:背景间歇性theta-burst刺激(iTBS)是重复性经颅磁刺激的一种形式,可能会改变初级体感皮层(SI)的皮质兴奋性。本研究调查了iTBS对左侧,iTBS刺激的SI和右半球非刺激SI记录的皮下和早期皮层体感诱发电位(SEP)的影响。在iTBS之前,之后的5、15和25分钟记录SEP。结果与iTBS前相比,非刺激性SI的皮层电位N20 / P25的幅度持续增加了5分钟,而刺激性SI的皮层电位N20 / P25的幅度增加了15至25分钟。 iTBS后,双侧记录的皮层下电位保持不变。结论我们得出的结论是,iTBS可以双向增加SI的皮质兴奋性,并且不会改变丘脑皮质向SI的传入输入。 ITBS可能提供一种在体感皮质中诱导皮质可塑性的途径。

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