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首页> 外文期刊>BMC Pediatrics >Gestational age at birth and behavioral problems from four to 11 years of age: birth cohort study
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Gestational age at birth and behavioral problems from four to 11 years of age: birth cohort study

机译：出生妊娠年龄和4至11岁的行为问题：出生队列研究

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Background Studies conducted mainly in high-income countries have shown that preterm births are associated with increased risk of behavioral problems and psychiatric disorders. The aim of this study was to assess the prevalence of behavioral problems from middle-childhood to early-adolescence according to gestational age at birth in a middle-income setting. Methods A population-based birth cohort ( n =?4231) in Pelotas, Brazil, was followed-up in several occasions from birth to 11?years. Estimated GA was based on last menstrual period or, when unknown or inconsistent, on the Dubowitz method. Behavioral problems were assessed at 4 (Child Behavior Checklist - CBCL), and at 6 and 11?years (Development and Well-Being Assessment - DAWBA) tool. Maternal socio-economic characteristics and depression at 2, 4 and 6?years post-partum, child perinatal characteristics and breastfeeding duration were used as confounders. Analyses were run by linear and logistic regression. Results Three thousand two hundred four children had full information on gestational age, CBCL and DAWBA. At 4?years, mean total (42.9?±?24.0) and mean externalizing (18.8?±?9.1) CBCL scores were higher among preterm girls born at Conclusion At this large cohort, behavioral problems from middle-childhood to early-adolescence are more related to family socio-economic characteristics and to other child perinatal conditions than to gestational age at birth.
机译：主要在高收入国家进行的背景研究表明，早产与行为问题和精神病风险增加有关。这项研究的目的是根据中等收入环境中出生时的胎龄来评估从童年中期到青春期的行为问题的普遍性。方法对巴西佩洛塔斯市一个以人口为基础的出生队列（n = 4231）进行了随访，从出生到11岁。估计的GA是基于上一次月经期，或者在未知或前后不一致时，以Dubowitz方法为基础。在4岁（儿童行为清单-CBCL），6岁和11岁（发育和幸福评估-DAWBA）工具下评估了行为问题。产妇在产后2、4和6年的社会经济特征和抑郁，儿童围产期特征和母乳喂养时间被用作混杂因素。通过线性和逻辑回归进行分析。结果3,204名儿童全面了解胎龄，CBCL和DAWBA。在4岁时，早产女婴的平均总CBCL分数（42.9±24.0）和平均外在化（18.8±9.1）较高。结论在这个大队列中，从中童到青春期的行为问题很严重。与出生时的胎龄相比，与家庭社会经济特征和其他儿童围产期疾病的关系更大。

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