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Echocardiographic pattern of rheumatic valvular disease in a contemporary sub-Saharan African pediatric population: an audit of a major cardiac ultrasound unit in Yaounde, Cameroon

机译:在当代撒哈拉以南非洲儿童人群中风湿性瓣膜疾病的超声心动图模式:对喀麦隆雅温得主要心脏超声检查单位的审计

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Background Rheumatic Heart Disease (RHD) remains a major cause of childhood acquired heart disease in developing countries. However reported echocardiographic features are limited to a few countries. This report is on the demographic and echocardiographic features of RHD in children using data from the largest referral hospital in Yaounde, the capital city of Cameroon. Methods The register of the cardiac ultrasound unit of the Yaounde General Hospital for the period 2003–2013 served as basis for data collection. RHD diagnosis was based on the World Heart Federation Criteria for the diagnosis of RHD. Demographic data, pattern of valve lesions and severity were analyzed. Results A total of 1130 first echocardiographic examinations were performed in children aged?≤?18?years. Sixty-five (5.8?%) had a definite echocardiographic diagnosis of RHD with their mean age being 11.8 years (SD 3.6) and 31 (47.1?%) being boys. The commonest primary reasons for requesting an echocardiographic examination were a clinical diagnosis of RHD (24.6?%) without heart failure, a clinical diagnosis of heart failure (24.6?%), and heart murmurs (21.5?%). Isolated mitral regurgitation was the most common valve lesion (49.2?%) and was frequently associated with aortic regurgitation (35.4?%). Severe lesions were found in 63.3?% of participants. No right heart lesion was reported. Conclusions A sizable proportion of children undergoing echocardiographic examination at this major referral hospital in Cameroon had RHD, with lesions found only on the left heart. These lesions predominated on the mitral valve, were commonly associated with aortic regurgitation, and more often severe.
机译:背景技术风湿性心脏病(RHD)仍然是发展中国家儿童后天性心脏病的主要原因。但是,报告的超声心动图特征仅限于少数国家。该报告使用喀麦隆首都雅温得最大的转诊医院的数据,对儿童的RHD进行了人口统计学和超声心动图检查。方法2003年至2013年期间,雅温得总医院心脏超声科的登记册是数据收集的基础。 RHD的诊断是基于《世界心脏联合会诊断RHD的标准》。分析了人口统计学数据,瓣膜病变的类型和严重程度。结果对≤≤18岁的儿童共进行了1130次首次超声心动图检查。六十五(5.8%)的患者明确诊断为RHD,其平均年龄为11.8岁(SD 3.6),其中31岁(47.1%)为男孩。要求进行超声心动图检查的最主要的主要原因是无心力衰竭的RHD临床诊断(24.6%),心力衰竭的临床诊断(24.6%)和心脏杂音(21.5%)。孤立性二尖瓣关闭不全是最常见的瓣膜病变(49.2%),并经常伴有主动脉关闭不全(35.4%)。在63.3%的参与者中发现了严重病变。没有右心病变的报道。结论在喀麦隆一家主要的转诊医院接受超声心动图检查的儿童中,有相当一部分患有RHD,仅在左心脏有病变。这些病变主要集中在二尖瓣上,通常与主动脉瓣关闭不全相关,并且更常见。

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