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Antidepressant and antipsychotic use in an Italian pediatric population

机译:意大利儿童人群的抗抑郁药和抗精神病药的使用

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Background The safety and effectiveness of psychotropic drug use in the paediatric population is widely debated, in particular because of the lack of data concerning long term effects. In Italy the prevalence of psychotropic drug prescriptions increased in the early 2000s and decreased afterwards. In such a context, a study with the aim to estimate the incidence and prevalence of psychotropic drug prescription in the paediatric population and to describe diagnostic and therapeutic approaches was performed. Methods The study population was composed of 76,000 youths less than 18 years and living in the area covered by the local health unit of Verona, Italy. The data source was the Verona local health unit's administrative prescription database. Prevalence and incidence of antidepressant and/or antipsychotic drug prescriptions in the 2004-2008 period were estimated. Children and adolescents receiving antidepressant and/or antipsychotic drug prescriptions between 1 January 2005 and 31 December 2006 were identified and questionnaires were sent to the prescribers with the aim to collect data concerning diagnostic and therapeutic approaches, and care strategies. Results The prevalence of psychotropic drug prescriptions did not change in the 2004-2008 period, while incidence slightly increased (from 7.0 in 2005 to 8.3 per 10,000 in 2008). Between 1 January 2005 and 31 December 2006, 111 youths received at least one psychotropic drug prescription, 91 of whom received antidepressants. Only 28 patients attended child and adolescent psychiatry services. Information concerning diagnostic and therapeutic approaches, and care strategies was collected for 52 patients (47%). Anxiety-depressive syndrome and attention disorders were the diseases for which psychotropic drugs were most commonly prescribed. In all, 75% youths also received psychological support and 20% were prescribed drugs for 2 or more years. Conclusions Despite the low drug prescription prevalence, the finding that most children were not cared for by child and adolescent psychiatric services is of concern and calls for a systematic, continuous monitoring of psychopharmacological treatments.
机译:背景技术精神药物在小儿人群中的安全性和有效性受到广泛争议,特别是因为缺乏有关长期影响的数据。在意大利,精神药物处方的患病率在2000年代初有所增加,此后有所下降。在这种情况下,进行了一项研究,目的是估计精神药物处方在儿科人群中的发生率和患病率,并描述诊断和治疗方法。方法研究对象为76,000名18岁以下的年轻人,居住在意大利维罗纳当地卫生所覆盖的地区。数据源是维罗纳地方卫生部门的行政处方数据库。估计2004-2008年期间抗抑郁药和/或抗精神病药处方的发生率和发生率。确定了2005年1月1日至2006年12月31日期间接受抗抑郁药和/或抗精神病药处方的儿童和青少年,并向处方者发送了问卷,目的是收集有关诊断和治疗方法以及护理策略的数据。结果2004年至2008年期间,精神药物处方的使用率未发生变化,但发病率略有增加(从2005年的7.0增加到2008年的10,000分之8.3)。在2005年1月1日至2006年12月31日期间,有111名青年接受了至少一种精神药物处方,其中91名接受了抗抑郁药治疗。只有28名患者参加了儿童和青少年精神病学服务。收集了有关52例患者(47%)的有关诊断和治疗方法以及护理策略的信息。焦虑抑郁综合症和注意力障碍是最常使用精神药物的疾病。总计,有75%的年轻人也获得了心理支持,有20%的人开了2年以上的处方药。结论尽管处方药的患病率较低,但发现大多数儿童没有得到儿童和青少年精神科服务的照顾值得关注,并要求对精神药物治疗进行系统,持续的监测。

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