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首页> 外文期刊>BMC Neuroscience >The correlation between motor impairments and event-related desynchronization during motor imagery in ALS patients
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The correlation between motor impairments and event-related desynchronization during motor imagery in ALS patients

机译：ALS患者运动成像期间运动障碍与事件相关失步之间的相关性

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Background The event-related desynchronization (ERD) in EEG is known to appear during motor imagery, and is thought to reflect cortical processing for motor preparation. The aim of this study is to examine the modulation of ERD with motor impairment in ALS patients. ERD during hand motor imagery was obtained from 8 ALS patients with a variety of motor impairments. ERD was also obtained from age-matched 11 healthy control subjects with the same motor task. The magnitude and frequency of ERD were compared between groups for characterization of ALS specific changes. Results The ERD of ALS patients were significantly smaller than those of control subjects. Bulbar function and ERD were negatively correlated in ALS patients. Motor function of the upper extremities did was uncorrelated with ERD. Conclusions ALS patients with worsened bulbar scales may show smaller ERD. Motor function of the upper extremities did was uncorrelated with ERD.
机译：背景技术EEG中的事件相关去同步（ERD）已知会在运动成像期间出现，并被认为反映了皮质运动以进行运动准备。这项研究的目的是检查ALS患者中ERD与运动障碍的关系。从8名具有各种运动障碍的ALS患者中获得了手部运动成像期间的ERD。还从具有相同运动任务的年龄匹配的11名健康对照受试者中获得了ERD。比较了两组之间ERD的大小和频率，以表征ALS特异性变化。结果ALS患者的ERD显着小于对照组。 ALS患者的球茎功能和ERD呈负相关。上肢的运动功能确实与ERD无关。结论ALS患者球囊鳞片恶化可能显示较小的ERD。上肢的运动功能确实与ERD无关。

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