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Parents' reported preference scores for childhood atopic dermatitis disease states

机译:父母报告的儿童特应性皮炎疾病状态的偏好分数

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Background We sought to elicit preference weights from parents for health states corresponding to children with various levels of severity of atopic dermatitis. We also evaluated the hypothesis that parents with children who had been diagnosed with atopic dermatitis would assign different preferences to the health state scenarios compared with parents who did not have a child with atopic dermatitis. Methods Subjects were parents of children aged 3 months to 18 years. The sample was derived from the General Panel, Mommies Sub-Panel, and Chronic Illness Sub-Panel of Harris Interactive. Participants rated health scenarios for atopic dermatitis, asthma, and eyeglasses on a visual analog scale, imagining a child was experiencing the described state. Results A total of 3539 parents completed the survey. Twenty-nine percent had a child with a history of atopic dermatitis. Mean preference scores for atopic dermatitis were as follows: mild, 91 (95% confidence interval [CI], 90.7 to 91.5); mild/moderate, 84 (95%CI, 83.5 to 84.4); moderate, 73 (95%CI, 72.5 to 73.6); moderate/severe, 61 (95%CI, 60.6 to 61.8); severe, 49 (95% CI, 48.7 to 50.1); asthma, 58 (95%CI, 57.4 to 58.8); and eyeglasses, 87(95%CI, 86.3 to 87.4). Conclusions Parents perceive that atopic dermatitis has a negative effect on quality of life that increases with disease severity. Estimates of parents' preferences can provide physicians with insight into the value that parents place on their children's treatment and can be used to evaluate new medical therapies for atopic dermatitis.
机译:背景技术我们试图从父母那里获得针对患有异位性皮炎严重程度不同的儿童的健康状况的优先权重。我们还评估了以下假设,即与没有患特应性皮炎的父母相比,被诊断患有特应性皮炎的儿童的父母会对健康状况的情景分配不同的偏好。方法受试者为3个月至18岁儿童的父母。样本来自Harris Interactive的“一般小组”,“妈妈”小组和“慢性病”小组。参与者以视觉模拟量表评估了特应性皮炎,哮喘和眼镜的健康状况,并想象孩子正在经历上述状态。结果共有3539名父母完成了调查。 29%的孩子有特应性皮炎病史。特应性皮炎的平均偏爱评分如下:轻度91分(95%置信区间[CI]为90.7至91.5);中度/中度84(95%CI,83.5至84.4);中度73(95%CI,72.5至73.6);中度/重度,61(95%CI,60.6至61.8);严重的为49(95%CI,48.7至50.1);哮喘58(95%CI,57.4至58.8);和眼镜,87(95%CI,86.3至87.4)。结论父母认为特应性皮炎对生活质量有负面影响,并随疾病严重程度而增加。估计父母的偏爱可以使医生深入了解父母对孩子的治疗的价值,并可用于评估特应性皮炎的新药物治疗。

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