Severe acquired cytomegalovirus infection in a full-term, formula-fed infant: Case Report

Alberto Berardi; Cecilia Rossi; Valentina Fiorini; Cristina Rivi; Federica Vagnarelli; Nicola Guaraldi; Paola Pietrosemoli; Tiziana Lazzarotto; Fabrizio Ferrari

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Severe acquired cytomegalovirus infection in a full-term, formula-fed infant: Case Report

机译：足月由配方奶喂养的婴儿中获得性巨细胞病毒严重感染：病例报告

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Background Cases of cytomegalovirus colitis are exceptionally reported in immuno-competent infant. The pathogenesis is uncertain but breast-feeding is considered as a main source of postnatal infection. Case Presentation Here we report a full-term, formula-fed infant who developed a severe cytomegalovirus anaemia and colitis when aged 2 months. Conclusion Even if the molecular identity between the cytomegalovirus-isolate of the infant and the maternal virus could not be demonstrated, we confirmed through laboratory investigation that cytomegalovirus infection was acquired postnatally. However, the source of cytomegalovirus infection remained unclear. Alternative modes of cytomegalovirus transmission are discussed.

机译：背景免疫功能正常的婴儿异常报道了巨细胞病毒性结肠炎的病例。发病机理尚不确定，但母乳喂养被认为是产后感染的主要来源。病例介绍这里我们报告一个足月的配方奶喂养的婴儿，该婴儿在两个月大时出现严重的巨细胞病毒性贫血和结肠炎。结论即使无法证明婴儿的巨细胞病毒分离株与母体病毒之间的分子同一性，我们也通过实验室研究证实了巨细胞病毒感染是在出生后获得的。但是，巨细胞病毒感染的来源仍不清楚。讨论了巨细胞病毒传播的其他方式。

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《BMC Pediatrics》 |2011年第1期|共页
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Alberto Berardi; Cecilia Rossi; Valentina Fiorini; Cristina Rivi; Federica Vagnarelli; Nicola Guaraldi; Paola Pietrosemoli; Tiziana Lazzarotto; Fabrizio Ferrari;
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1. Severe postnatally acquired cytomegalovirus infection presenting with colitis, pneumonitis and sepsis-like syndrome in an extremely low birthweight infant. [J] . Fischer C, Meylan P, Bickle Graz M, Neonatology . 2010,第4期

机译：出生体重极低的婴儿在出生后严重感染巨细胞病毒，并伴有结肠炎，肺炎和败血症样综合征。
2. Congenital Cytomegalovirus Infection Causing severe Inclusion Diseases in Infants - Case Report from Eastern India [J] . Aroni Chatterjee, Agniswar Sarkar, Rajendra Prasad Chatterjee, International Research Journal of Biological Sciences . 2016,第12期

机译：先天性巨细胞病毒感染导致婴儿严重包涵体疾病-印度东部病例报告
3. Congenital cytomegalovirus infection in preterm and full-term newborn infants from a population with a high seroprevalence rate. [J] . Yamamoto AY, Mussi-Pinhata MM, Cristina P, The Pediatric infectious disease journal . 2001,第2期

机译：血清流行率高的早产儿和足月儿的先天性巨细胞病毒感染。
4. Prevalence and Clinical Spectrum of Cytomegalovirus Infection in Newborns and Infants [C] . CM. Mihai, R. Stoicescu, L. Mihai, European Congress of Perinatal Medicine . 2008

机译：新生儿和婴幼儿患有缩细胞病毒感染的患病率与临床谱
5. Characterizing accidents, exposures, and laboratory-acquired infections reported to the national institutes of health's office of biotechnology activities (NIH/OBA) involving recombinant DNA biological agents. [D] . Campbell, Mark J. 2014

机译：向国家卫生研究院生物技术活动办公室（NIH / OBA）报告涉及重组DNA生物制剂的事故，暴露和实验室获得的感染的特征。
6. Severe acquired cytomegalovirus infection in a full-term formula-fed infant: Case Report [O] . Alberto Berardi, Cecilia Rossi, Valentina Fiorini, 2011

机译：足月由配方奶喂养的婴儿中获得性巨细胞病毒严重感染：病例报告
7. Severe acquired cytomegalovirus infection in a full-term, formula-fed infant: Case Report [O] . 2011

机译：足月由配方奶喂养的婴儿中获得性巨细胞病毒严重感染：病例报告
8. Development of Antiviral Drugs for Treatment of Cytomegalovirus (CMV) Infections, Particularly in AIDS (Acquired Immuno-Deficiency Syndrome) and Other Immunosuppressed Patients. Annual Report July 1, 1985-June 30, 1986 [R] . Wright, G. E. , Medveczky, P. 1986

机译：用于治疗巨细胞病毒（CmV）感染的抗病毒药物的开发，特别是在艾滋病（获得性免疫缺陷综合症）和其他免疫抑制患者中。年报1985年7月1日至1986年6月30日

Severe acquired cytomegalovirus infection in a full-term, formula-fed infant: Case Report

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