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Acute disseminated encephalomyelitis presenting as fever of unknown origin: case report

机译:急性弥漫性脑脊髓炎表现为来历不明的发热:病例报告

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Background Fever of unknown origin (FUO) can be defined as a body temperature higher than 38.3°C on several occasions over more than 3 weeks, the diagnosis of which remains uncertain after 1 week of evaluation. Acute disseminated encephalomyelitis (ADEM) is an inflammatory demyelinating disease of the central nervous system with a wide range of clinical manifestations. The highest incidence of ADEM is observed during childhood and it usually occurs following a viral or bacterial infection or, more rarely, following a vaccination, or without a preceding cause. Case presentation Here, we describe an atypical case of ADEM that initially manifested as several weeks of FUO in a fifteen years old boy. Conclusions This case report suggests a new possible syndromic association between ADEM and FUO, which should be considered in the clinical examination of patients with FUO, especially in the presence of also modest neurologic or neuropsychiatric symptoms.
机译:背景未知来源的发烧(FUO)可以定义为在超过3周的多次时间内体温高于38.3°C,在评估1周后仍不确定诊断。急性播散性脑脊髓炎(ADEM)是中枢神经系统的炎症性脱髓鞘疾病,具有广泛的临床表现。 ADEM的发病率最高,发生在儿童时期,通常发生在病毒或细菌感染后,或更罕见的是在接种疫苗后或无前因。病例介绍在这里,我们描述了一个非典型的ADEM病例,最初在15岁的男孩中表现为几周的FUO。结论本病例报告提示ADEM与FUO之间可能存在新的症状关联,在FUO患者的临床检查中应考虑这一关联,尤其是在存在中度神经系统或神经精神症状的情况下。

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