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Health state preferences associated with weight status in children and adolescents

机译:与儿童和青少年体重状况相关的健康状况偏好

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Background Childhood obesity is a substantial public health problem. The extent to which health state preferences (utilities) are related to a child's weight status has not been reported. The aims of this study were (1) to use a generic health state classification system to measure health related quality of life and calculate health utilities in a convenience sample of children and adolescents and (2) to determine the extent to which these measures are associated with weight status and body mass index (BMI). Methods We enrolled 76 children 5-18 years of age from a primary care clinic and an obesity clinic in Boston MA. We administered the Health Utilities Index (HUI) and used the HUI Mark 3 single- and multi-attribute utility functions to calculate health utilities. We determined BMI percentile and weight status based on CDC references. We examined single-attribute and overall utilities in relation to weight status and BMI. Results Mean (range) age was 10.8 (5-18) years. Mean (SD) BMI percentile was 76 (26); 55% of children were overweight or obese. The mean (SD) overall utility was 0.79 (0.17) in the entire sample. For healthy-weight children, the mean overall utility was higher than for overweight or obese children (0.81 vs. 0.78), but the difference was not statistically significant (difference 0.04, 95% CI -0.04, 0.11). Conclusions Our results provide a quantitative estimate of the health utility associated with overweight and obesity in children, and will be helpful to researchers performing cost effectiveness analyses of interventions to prevent and/or treat childhood obesity.
机译:背景技术儿童肥胖是一个重大的公共卫生问题。尚未报告健康状况偏好(实用程序)与儿童体重状况相关的程度。这项研究的目的是(1)使用通用的健康状态分类系统来测量与健康相关的生活质量并计算儿童和青少年便利样本中的健康效用,以及(2)确定与这些措施相关的程度体重状态和体重指数(BMI)。方法我们在马萨诸塞州波士顿市的一家初级保健诊所和一个肥胖诊所招募了76名5-18岁的儿童。我们管理了Health Utilities Index(HUI),并使用了HUI Mark 3单属性和多属性Utility函数来计算Health Utility。我们根据CDC参考资料确定了BMI百分位数和体重状况。我们研究了与体重状况和BMI有关的单一属性和整体效用。结果平均(范围)年龄为10.8(5-18)岁。 BMI平均值(SD)为76(26); 55%的儿童超重或肥胖。在整个样本中,平均(SD)总体效用为0.79(0.17)。对于健康体重的儿童,平均总体效用高于超重或肥胖的儿童(0.81比0.78),但差异无统计学意义(差异0.04,95%CI -0.04,0.11)。结论我们的结果提供了与儿童超重和肥胖有关的健康效用的定量估计,并将有助于研究人员进行预防和/或治疗儿童肥胖的干预措施的成本效益分析。

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