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Ovarian carcinoma associated with pregnancy: A clinicopathologic analysis of 23 cases and review of the literature

机译：卵巢癌合并妊娠：23例临床病理分析及文献复习

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Background The aim of this study was to analyze and describe cases of ovarian cancer in pregnant women treated at our center and to review the literature concerned, and to discuss the rationale for therapy. Methods Twenty-Three patients of ovarian malignancies during pregnancy were treated at Vali- Asr Hospital between 1991 and 2002. Data on treatment and follow-up were evaluated. Results The incidence of ovarian carcinoma associated with pregnancy in our series was 0.083/1000 deliveries. Eleven (47.8%) were found with ovarian malignant germ cell tumors, five (21.7%) with low malignant potential tumors, four (17.4%) with invasive epithelial tumors, and three (13%) with sex cord stromal tumors. Seventeen (73.9%) of the patients were diagnosed in stage I and had complete remission. Five of the six in advanced stage died. The mean follow-up was 36.3 months. The prognosis was significantly related with stage and histological type (P Conclusion Early finding of ascitis by ultrasound and persistent large ovarian mass during pregnancy may be related to malignancy and advanced stage. Pregnant women in advanced stage of ovarian cancer seem to have poor prognosis.
机译：背景技术这项研究的目的是分析和描述在我们中心接受治疗的孕妇的卵巢癌病例，并复习有关文献，并讨论治疗的理由。方法1991年至2002年间在Vali-Asr医院对23例妊娠期卵巢恶性肿瘤患者进行了治疗，并对其治疗和随访资料进行了评估。结果我们系列中与妊娠相关的卵巢癌发生率为0.083 / 1000分娩。卵巢恶性生殖细胞肿瘤发现11例（47.8％），恶性潜能低的肿瘤发现5例（21.7％），浸润性上皮性肿瘤发现4例（17.4％），性索间质肿瘤发现3例（13％）。十七名患者（73.9％）被诊断为I期并已完全缓解。六个晚期中有五个死亡。平均随访36.3个月。预后与分期和组织学类型显着相关（P结论超声检查早发现腹水和持续的大卵巢肿块可能与恶性肿瘤和晚期有关。晚期卵巢癌的孕妇预后较差。

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