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首页> 外文期刊>BMC Psychiatry >Seasonality in depressive and anxiety symptoms among primary care patients and in patients with depressive and anxiety disorders; results from the Netherlands Study of Depression and Anxiety
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Seasonality in depressive and anxiety symptoms among primary care patients and in patients with depressive and anxiety disorders; results from the Netherlands Study of Depression and Anxiety

机译：初级保健患者以及患有抑郁和焦虑症的患者的抑郁和焦虑症状的季节性;荷兰抑郁症和焦虑症研究的结果

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Background Little is known about seasonality of specific depressive symptoms and anxiety symptoms in different patient populations. This study aims to assess seasonal variation of depressive and anxiety symptoms in a primary care population and across participants who were classified in diagnostic groups 1) healthy controls 2) patients with a major depressive disorder, 3) patients with any anxiety disorder and 4) patients with a major depression and any anxiety disorder. Methods Data were used from the Netherlands Study of Depression and Anxiety (NESDA). First, in 5549 patients from the NESDA primary care recruitment population the Kessler-10 screening questionnaire was used and data were analyzed across season in a multilevel linear model. Second, in 1090 subjects classified into four groups according to psychiatric status according to the Composite International Diagnostic Interview, overall depressive symptoms and atypical versus melancholic features were assessed with the Inventory of Depressive Symptoms. Anxiety and fear were assessed with the Beck Anxiety Inventory and the Fear questionnaire. Symptom levels across season were analyzed in a linear regression model. Results In the primary care population the severity of depressive and anxiety symptoms did not show a seasonal pattern. In the diagnostic groups healthy controls and patients with any anxiety disorder, but not patients with a major depressive disorder, showed a small rise in depressive symptoms in winter. Atypical and melancholic symptoms were both elevated in winter. No seasonal pattern for anxiety symptoms was found. There was a small gender related seasonal effect for fear symptoms. Conclusions Seasonal differences in severity or type of depressive and anxiety symptoms, as measured with a general screening instrument and symptom questionnaires, were absent or small in effect size in a primary care population and in patient populations with a major depressive disorder and anxiety disorders.
机译：背景对于不同患者人群中特定的抑郁症状和焦虑症状的季节性知之甚少。这项研究旨在评估在初级保健人群和诊断组中分为1）健康对照2）患有重度抑郁症的患者，3）患有焦虑症的患者和4）患者的抑郁和焦虑症状的季节性变化患有严重的抑郁症和任何焦虑症。方法数据来自荷兰抑郁症和焦虑症研究（NESDA）。首先，在NESDA初级保健招募人群中的5549例患者中，使用了Kessler-10筛查问卷，并在一个多层线性模型中分析了整个季节的数据。其次，根据《综合国际诊断访谈》将1090名根据精神状态分为四类的受试者，通过抑郁症状量表评估了总体抑郁症状以及非典型与忧郁特征。用贝克焦虑量表和恐惧问卷评估焦虑和恐惧。使用线性回归模型分析整个季节的症状水平。结果在初级保健人群中，抑郁和焦虑症状的严重程度没有显示出季节性变化。在诊断组中，健康对照者和任何焦虑症患者，但重度抑郁症患者则没有，冬季的抑郁症状略有上升。冬季非典型和忧郁症状均升高。没有发现焦虑症状的季节性模式。恐惧症状对性别的影响很小。结论抑郁症和焦虑症的严重程度或类型的季节性差异（通过常规筛查仪器和症状问卷调查得出）在初级保健人群和患有严重抑郁症和焦虑症的患者人群中，其影响大小不存在或影响较小。

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