• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>BMC Psychiatry >Associations of mood symptoms with NYHA functional classes in angina pectoris patients: a cross-sectional study
【24h】

Associations of mood symptoms with NYHA functional classes in angina pectoris patients: a cross-sectional study

机译：心绞痛患者情绪症状与NYHA功能分类的关联：一项横断面研究

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Depression and anxiety are prevalent and associated with a worse prognosis in coronary heart disease (CHD) patients. However, the influence of disease severity on mood symptoms is unknown. The specific associations of mood symptoms with NYHA classes remain unexplored. In this cross-sectional study, 443 consecutive inpatients with angina pectoris (AP) confirmed by angiography were included into analysis. Somatic and cognitive symptom scores derived from Patient Health Questionnaire (PHQ-9) and Generalized Anxiety Disorder Scale (GAD-7) were used to assess mood symptoms. Predictors for depression and anxiety with strict and lax standards were compared. We hypothesized NYHA classification to be an indicator of disease severity through analyses with clinical features using ordinal logistic model. Applying both binary and ordinal logistic models, we evaluated the associations of mood symptoms with NYHA classes. Discrepancy of disease severity existed between the depressed and nondepressed. NYHA classification was proved to be an integrated index under influence of age, coronary stenosis, heart failure and diabetes. NYHA class I and II individuals with AP were at equivalent risk for depression (NYHA II vs I: binary model OR 1.32 (0.59,2.96), p?=?0.50; ordinal model OR 1.17 (0.73,1.88), p?=?0.52), however NYHA class III/IV patients shared a sharply higher risk (NYHA III/IV vs I: binary model OR 3.32 (1.28,8.61), p?=?.013; ordinal model OR 3.94 (2.11,7.36), p??.001). Analyses on somatic and cognitive depressive symptoms confirmed this finding and hinted a greater impact of education background on mood when patient’s condition is unstable. Anxiety seemed in the whole picture irrelevant with NYHA classes. Comparing with NYHA class I/II, AP patients in NYHA class III/IV tended to be less anxious. However, when CHD became unstable, the calmness may immediately be broken up. A great distinction of the ratio of anxiety and depression symptom scores between NYHA class III/IV stable and unstable AP patients (p?=?.018) was observed. Mood symptoms in CHD patients are to a great extend derived from disease itself. Only for patients with relatively serious physical condition, unexpected discomforts caused by disease notably impact the emotions. Education background tends to influence the mood especially when disease is still unstable.
机译：抑郁症和焦虑症很普遍，并且与冠心病（CHD）患者的预后较差有关。但是，疾病严重程度对情绪症状的影响尚不清楚。情绪症状与NYHA类别的具体关联尚待探索。在这项横断面研究中，将443例经血管造影确诊的心绞痛（AP）住院患者纳入分析。使用来自患者健康问卷（PHQ-9）和广义焦虑症量表（GAD-7）的躯体和认知症状评分来评估情绪症状。比较了严格和宽松标准下抑郁和焦虑的预测指标。通过使用序数逻辑模型对临床特征进行分析，我们假设NYHA分类是疾病严重程度的指标。应用二元和序数逻辑模型，我们评估了情绪症状与NYHA类别的关联。抑郁和非抑郁之间存在疾病严重程度的差异。事实证明，NYHA分类是受年龄，冠状动脉狭窄，心力衰竭和糖尿病影响的综合指标。患有AP的NYHA I级和II级个体患抑郁症的风险相同（NYHA II与I级：二元模型OR 1.32（0.59,2.96），p <= 0.50;顺序模型OR 1.17（0.73,1.88），p <= 0.52），但是NYHA III / IV级患者的风险明显更高（NYHA III / IV vs I：二元模型OR 3.32（1.28,8.61），p？= ?. 013;顺序模型OR 3.94（2.11,7.36）， p？

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号