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首页> 外文期刊>BMC Psychiatry >Buprenorphine maintenance program with contracted work/education and low tolerance for non-prescribed drug use: a cohort study of outcome for women and men after seven years
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Buprenorphine maintenance program with contracted work/education and low tolerance for non-prescribed drug use: a cohort study of outcome for women and men after seven years

机译:丁丙诺啡维持计划,具有合同规定的工作/教育和对非处方药物使用的低耐受性:一项针对七年后男女结果的队列研究

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A seven-year follow-up of heroin dependent patients treated in a buprenorphine-maintenance program combining contracted work/education and low tolerance for non-prescribed drug use. Gender-specific differences in outcome were analysed. A consecutively admitted cohort of 135 men and 35 women, with eight years of heroin abuse/dependence on average was admitted to enhanced buprenorphine maintenance treatment. Standardized interviews, diagnostic assessments of psychiatric disorders and psychosocial conditions were conducted at admission and at follow-ups. Outcome associated with gender was reported for abstinence, retention, psychiatric symptoms, employment and criminal convictions. 148 patients started treatment. After seven years, 94/148 patients (64%) were retained in the program, employed and abstinent from drugs and alcohol. Women had more continuous abstinence, retention and employment than men (76% versus 60%). After one year patients with a high-risk consumption of alcohol were no longer heavy consumers of alcohol and remained so throughout the study (p?
机译:在丁丙诺啡维持计划中对海洛因依赖患者进行了为期7年的随访,该计划结合了合同规定的工作/教育和对非处方药物使用的低耐受性。分析了性别的结局差异。连续入组的135名男性和35名女性,平均滥用海洛因8年/依赖海洛因,被接受加强丁丙诺啡维持治疗。在入院时和随访时进行了标准化的访谈,精神障碍和社会心理状况的诊断评估。据报告与性别有关的结果包括节制,保留,精神病症状,就业和刑事定罪。 148例患者开始治疗。七年后,有94/148名患者(64%)被保留在该计划中,并被雇用和戒毒和戒酒。妇女的持续禁欲,保留和就业比男子多(76%比60%)。一年后,高风险饮酒的患者不再是大量饮酒的人,并且在整个研究过程中仍然如此(p <0.001)。所有妇女都重新获得了对子女的监护权。入院时,接受精神疾病和强制性药物滥用护理的妇女(70%/ 44%)多于男性(30%/ 18%)。精神病合并症的最初性别差异减少,一年后不再显着。在非机构护理中,被监禁的男性比女性多(62%比27%)(80%比49%)。七年后,刑事定罪从入院时的1751起减少到742起(58%)。整个队列中有8名患者在7年内死亡(每年0.7%)。在完成程序组中,有一名患者在完成程序组中死亡(每年0.1%)。七年后,该计划中有三分之二的患者被戒断并被雇用。对完成者小组的定罪停止了。一名患者在完成组中死亡。与男性相比,女性的长期结果更好:持续的禁欲,就业和定罪更少。妇女与子女一起生活的程度也高于男子。积极的结果突出了保持药物治疗与就业和心理治疗以及对非处方药的低耐受性相结合的高结构的重要性。

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