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The effects of acute and elective cardiac surgery on the anxiety traits of patients with Marfan syndrome

机译:急诊和择期心脏手术对马凡综合征患者焦虑性状的影响

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Background Marfan syndrome is a genetic disease, presenting with dysfunction of connective tissues leading to lesions in the cardiovascular and skeletal muscle system. Within these symptoms, the most typical is weakness of the connective tissue in the aorta, manifesting as aortic dilatation (aneurysm). This could, in turn, become annuloaortic ectasia, or life-threatening dissection. As a result, life-saving and preventative cardiac surgical interventions are frequent among Marfan syndrome patients. Aortic aneurysm could turn into annuloaortic ectasia or life-threatening dissection, thus life-saving and preventive cardiac surgical interventions are frequent among patients with Marfan syndrome. We hypothesized that patients with Marfan syndrome have different level of anxiety, depression and satisfaction with life compared to that of the non-clinical patient population. Methods Patients diagnosed with Marfan syndrome were divided into 3 groups: those scheduled for prophylactic surgery, those needing acute surgery, and those without need for surgery ( n =?9, 19, 17, respectively). To examine the psychological features of the patients, Spielberger’s anxiety (STAI) test, Beck’s Depression questionnaire (BDI), the Berne Questionnaire of Subjective Well-being, and the Satisfaction with Life scale were applied. Results A significant difference was found in trait anxiety between healthy individuals and patients with Marfan syndrome after acute life-saving surgery ( p p >?0.1). Finally, a significant, medium size effect was found between patient groups on the Joy in Living scale (F (2.39)?=?3.51, p =?0.040, η2?=?0.15). Conclusions Involving psychiatric and mental-health care, in addition to existing surgical treatment interventions, is essential for more successful recovery of patients with Marfan syndrome.
机译:背景技术马凡氏综合症是一种遗传性疾病,表现为结缔组织功能障碍,导致心血管和骨骼肌系统受损。在这些症状中,最典型的是主动脉的结缔组织无力,表现为主动脉扩张(动脉瘤)。反过来,这可能会成为无主动脉扩张或威胁生命的解剖。结果,在马凡综合症患者中经常进行挽救生命和预防性心脏外科手术。主动脉瘤可能转变为瓣环扩张或危及生命的夹层,因此在马凡氏综合征患者中经常进行挽救生命和预防性心脏外科手术。我们假设,与非临床患者相比,马凡氏综合征患者的焦虑,抑郁和生活满意度不同。方法将诊断为马凡氏综合症的患者分为三类:计划进行预防性手术的患者,需要急性手术的患者和不需要手术的患者(n = 9、19、17)。为了检查患者的心理特征,应用了斯皮尔伯格焦虑(STAI)测试,贝克抑郁问卷(BDI),伯恩主观幸福感问卷以及对生活的满意度量表。结果急性抢救性手术后,健康人与马凡氏综合征患者的性格焦虑差异显着(p p>?0.1)。最后,在患者的“生活中快乐”量表上发现了中等大小的显着效果(F(2.39)?=?3.51,p =?0.040,η 2 ?=?0.15)。结论除了现有的外科手术干预措施外,涉及精神病和心理健康护理对于使马凡氏综合症患者更成功地康复至关重要。

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