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首页> 外文期刊>BMC Psychiatry >Psychotropic medication use among patients with celiac disease
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Psychotropic medication use among patients with celiac disease

机译：乳糜泻患者中使用精神药物

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Celiac disease is a multi-system disorder with manifestations that may result in psychiatric disorders. We assessed the prevalence of medication use to treat psychiatric disorders in celiac disease patients. We conducted a cross-sectional study of patients undergoing esophagogastroduodenoscopy over 9-years at a celiac disease referral center. We compared the prevalence of psychotropic medication use among celiac disease patients (n?=?1293) to a control group (n?=?1401) with abdominal pain or reflux. Among all patients the mean age was 48.4?years, most were female (69.5%), and 22.7% used any psychotropic medication. There was no difference between overall psychotropic medication use among celiac disease patients and controls (23.9% vs 21.8%, OR 1.16; 95% CI 0.96–1.39, p?=?0.12). However, those with celiac disease were more likely to use antidepressants on univariate (16.4% vs 13.4%, p?=?0.03) and multivariate analysis (OR 1.28; 95% CI 1.03–1.59; p?=?0.03). Use of psychotropic medications was not associated with disease duration or mode of presentation of celiac disease. Celiac disease patients use psychotropic medications at similar rates as those with other gastrointestinal diseases, though subgroup analysis suggests they may use more antidepressants. Future studies should investigate whether celiac disease is associated with mood disorders that are not treated with medications.
机译：腹腔疾病是一种多系统疾病，其表现可能导致精神疾病。我们评估了治疗腹腔疾病患者精神疾病的药物使用率。我们对腹腔疾病转诊中心接受食管胃十二指肠镜检查超过9年的患者进行了横断面研究。我们将腹腔疾病患者（n = 1293）与腹痛或反流的对照组（n = 1401）的精神药物使用率进行了比较。在所有患者中，平均年龄为48.4岁，大多数为女性（69.5％），并且22.7％使用过任何精神药物。腹腔疾病患者和对照组的整体精神科药物使用之间没有差异（23.9％vs 21.8％，OR 1.16; 95％CI 0.96-1.39，p == 0.12）。然而，患有腹腔疾病的人更有可能在单变量（16.4％比13.4％，p <= 0.03）和多变量分析（OR 1.28; 95％CI 1.03-1.59; p == 0.03）上使用抗抑郁药。精神药物的使用与疾病持续时间或腹腔疾病的表现方式无关。腹腔疾病患者使用精神药物的比率与其他胃肠道疾病相似，尽管亚组分析表明他们可能使用更多的抗抑郁药。未来的研究应调查腹腔疾病是否与未经药物治疗的情绪障碍有关。

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