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An internet-based intervention for people with psychosis (EviBaS): study protocol for a randomized controlled trial

机译：基于互联网的精神病患者干预措施（EviBaS）：一项随机对照试验的研究方案

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Evidence shows that internet-based self-help interventions are effective in reducing symptoms for a wide range of mental disorders. To date, online interventions treating psychotic disorders have been scarce, even though psychosis is among the most burdensome disorders worldwide. Furthermore, the implementation of cognitive-behavioral therapy (CBT) for psychosis in routine health care is challenging. Internet-based interventions could narrow this treatment gap. Thus, a comprehensive CBT-based online self-help intervention for people with psychosis has been developed.?The aim of this study is the evaluation of the feasibility and efficacy of the intervention compared with a waiting list control group. The intervention includes modules on delusion, voice hearing, social competence, mindfulness, and seven other domains. Participants are guided through the program by a personal moderator. Usage can be amended by an optional smartphone app. In?this randomized controlled trial, participants are allocated to a waiting list or an intervention?of eight weeks. Change in positive psychotic symptoms of both groups will be compared (primary outcome) and predictors of treatment effects will be assessed. To our knowledge, this project is one of the first large-scale investigations of an internet-based intervention for people with psychosis. It may thus be a further step to broaden treatment options for people suffering from this disorder. NCT02974400 (clinicaltrials.gov), date of registration: November 28th 2016.
机译：有证据表明，基于互联网的自助干预措施可以有效减轻各种精神障碍的症状。迄今为止，尽管精神病是世界上最繁重的疾病之一，但治疗精神病的在线干预措施仍然很少。此外，在常规卫生保健中对精神病实施认知行为疗法（CBT）具有挑战性。基于互联网的干预措施可以缩小这种治疗差距。因此，已经开发出了一种基于CBT的综合性精神病患者在线自助干预措施。本研究的目的是与等待名单对照组相比，评估该干预措施的可行性和有效性。干预措施包括有关妄想，声音听觉，社交能力，正念和其他七个领域的模块。参与者由个人主持人指导整个计划。可以通过可选的智能手机应用程序修改使用情况。在这项随机对照试验中，参与者被分配到八周的等待名单或干预中。将比较两组的积极精神病症状的变化（主要结果），并评估治疗效果的预测指标。据我们所知，该项目是对基于互联网的精神病患者干预的首批大规模调查之一。因此，这可能是进一步扩展针对该疾病患者的治疗选择的步骤。 NCT02974400（clinicaltrials.gov），注册日期：2016年11月28日。

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