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首页> 外文期刊>Brazilian Journal of Otorhinolaryngology >Bayesian analysis of high-resolution ultrasonography and guided fine needle aspiration cytology in diagnosis of palpable thyroid nodules ☆
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Bayesian analysis of high-resolution ultrasonography and guided fine needle aspiration cytology in diagnosis of palpable thyroid nodules ☆

机译：高分辨率超声和引导下细针穿刺细胞学的贝叶斯分析在可触及甲状腺结节的诊断中的作用☆

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Introduction To evaluate diagnostic accuracy of high-resolution ultrasonography in differentiation of benign and malignant thyroid nodules in comparison to results of guided fine needle aspiration cytology based on the Bayes rule. Objective To assess the validity of ultrasonography results of thyroid nodules in comparison to guided fine needle aspiration cytology findings. Methods This study was done on randomly chosen 80 patients presented with palpable thyroid nodules, undergone real-time sonographic evaluation of thyroid nodules to characterize features, internal consistency, margins, echotexture, calcification, peripheral lucent halo and vascularity. Ultrasonography guided fine needle aspiration cytology studies of thyroid nodules were done. Results Palpable thyroid nodules were highly prevalent in fourth and fifth decades of life with female-male ratio, 4:1. Solid internal consistency was demonstrated by 75% malignant nodules. Hypoechogenicity and intra-nodular micro-calcifications were observed in 92% malignant nodules; 83% malignant nodules had intra-nodular vascularity and absence of peripheral halo. The pre-test prevalence of malignant nodules in the targeted population was 17.5%. As type I error, 2.5% false-positive cases and as type II error, 5.0% false-negative cases were detected. Values of sensitivity and specificity of the ultrasonography test were 71.43 and 96.97%, respectively. Conclusion Malignant thyroid nodules demonstrated ultrasonography characteristics of hypoechoic texture, intra-nodular micro-calcifications, solid consistency, internal vascularity and absence of peripheral halo. The ultrasonography test has 92.5% diagnostic accuracy to differentiate malignant from benign lesions in comparison to the gold standard fine needle aspiration cytology test.
机译：简介与基于贝叶斯规则的细针穿刺细胞学检查的引导结果相比，评估高分辨率超声检查对甲状腺良恶性结节的诊断准确性。目的评估甲状腺结节的超声检查结果与指导的细针穿刺细胞学检查结果相比的有效性。方法本研究是对随机选择的80例甲状腺结节患者进行实时超声检查，以表征其特征，内部一致性，切缘，回声纹理，钙化，外周光晕和血管性。超声引导下甲状腺结节细针穿刺细胞学研究。结果甲状腺结节可触及的甲状腺癌在生命的第四个和第五个十年十分普遍，男女比例为4：1。 75％的恶性结节显示出坚实的内部一致性。在92％的恶性结节中观察到了低软骨形成性和结节内微钙化。 83％的恶性结节具有结节内血管形成，并且周围无环晕。在目标人群中，恶性结节的测试前患病率为17.5％。作为I型错误，检出假阳性的病例为2.5％，作为II型错误，检出假阴性的病例为5.0％。超声检查的敏感性和特异性值分别为71.43和96.97％。结论甲状腺恶性结节表现为低回声纹理，结节内微钙化，固体稠度，内部血管分布和周围无光晕的超声特征。与金标准细针穿刺细胞学检查相比，超声检查具有92.5％的诊断准确性，可区分恶性和良性病变。

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