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首页> 外文期刊>Brazilian Journal of Otorhinolaryngology >25 (OH) D3 levels, incidence and recurrence of different clinical forms of benig paroxysmal positional vertigo ☆
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25 (OH) D3 levels, incidence and recurrence of different clinical forms of benig paroxysmal positional vertigo ☆

机译：25（OH）D3水平，良性阵发性位置性眩晕的不同临床形式的发生率和复发率☆

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Introduction Benign paroxysmal positional vertigo is the most common cause of dizziness in the general population. It is a condition with potential impact of reduced levels of vitamin D on its recurrent attacks. Objectives The aim of this study was to measure the serum levels of 25-hydroxyvitamin D3 (25-OH D3) in patients with benign paroxysmal positional vertigo and determine whether there is a difference in the serum levels of vitamin D3 between patients with and without recurrence, as well as between the different clinical forms of benign paroxysmal positional vertigo. Methods The study included 40 patients who came to the regular medical examination, diagnosed with posterior canal-benign paroxysmal positional vertigo based on the positive Dix-Hallpike's test. All patients underwent Epley manoeuvre after the diagnosis. Patients were classified according to current guidelines for levels of vitamin D3 in the serum in three groups: the deficiency, insufficiency and adequate level. Results The average serum level of 25-OH D3 among respondents was 20.78 ng/mL, indicating a lack or insufficiency of the aforementioned 25-OH D3. According to the levels of 25-OH D3, most patients suffer from deficiency (47.5%). 7 (17.5%) respondents had adequate blood level of 25-OH D3, and 14 (35%) respondents suffer from insufficiency. A significant difference was not found in the serum level of 25-OH D3 between patients with and without benign paroxysmal positional vertigo recurrence. There was a significant difference in the serum levels of 25-OH D3 in comparison to the clinical form of the disease. Lower 25-OH D3 values were found in patients with canalithiasis compared to those with cupulolithiasis. Conclusions There were no significant differences in the vitamin D3 serum level in patients with and without recurrence. The study showed a low level of serum vitamin D3 in most patients, indicating the need for supplemental therapy.
机译：简介良性阵发性位置性眩晕是普通人群中头晕的最常见原因。维生素D含量降低对其反复发作具有潜在影响。目的本研究的目的是测定良性阵发性位置性眩晕患者的血清25-羟基维生素D3（25-OH D3）的水平，并确定是否存在复发性和未复发患者的维生素D3血清水平存在差异以及良性阵发性位置性眩晕的不同临床形式之间。方法该研究纳入了40名接受常规体检的患者，根据Dix-Hallpike阳性检查诊断为后管良性阵发性位置性眩晕。诊断后所有患者均接受Epley手术。根据目前的指南，将患者的血清维生素D3水平分为三类：缺乏，不足和足够水平。结果受访者的25-OH D3的平均血清水平为20.78 ng / mL，表明上述25-OH D3的缺乏或不足。根据25-OH D3的水平，大多数患者患有缺乏症（47.5％）。 7名（17.5％）受访者血液中含25-OH D3足够，而14名（35％）受访者患有供血不足。在有和没有良性阵发性位置性眩晕复发的患者之间，血清25-OH D3水平未发现显着差异。与该疾病的临床形式相比，血清25-OH D3有显着差异。与患有结石症的患者相比，患有白痴症的患者的25-OH D3值较低。结论复发性和非复发性患者的维生素D3血清水平无显着差异。该研究表明，大多数患者的血清维生素D3含量较低，表明需要补充治疗。

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