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首页> 外文期刊>Brazilian Archives of Biology and Technology >Liver morphology and morphometry and plasma biochemical parameters of Wistar rats that received leaf infusion of Rudgea viburnoides Benth. (Rubiaceae)
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Liver morphology and morphometry and plasma biochemical parameters of Wistar rats that received leaf infusion of Rudgea viburnoides Benth. (Rubiaceae)

机译：Wistar大鼠的叶片形态输注Rudgea viburnoides Benth的肝脏形态，形态和血浆生化参数。 （菊科）

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摘要

Rudgea viburnoides leaves are widely used in popular Brazilian medicine as a diuretic, antirheumatic, hypotensive and blood depurative tea. The present study was carried out to investigate the effects of this infusion on the liver and on the plasma biochemical parameters of Wistar rats. Two groups received the R. viburnoides leaf infusion at a daily dose of 10 or 20g dry-leaves/L water, during 40 days. The histopathological analysis did not show degenerated areas or infiltration of leucocytes. Hepatic morphometry showed accumulation of fat in the hepatocytes of the treated groups. There was no significant change in the plasma levels of urea, creatinin, uric acid, direct bilirubin, cholesterol, total proteins, albumin, gamma glutamyl tranferase (gamma-GT), alanine transaminase (ALT), aspartate transaminase (AST), chlorine, phosphate and calcium. A significant reduction in the plasma levels of triacylglycerol (TAG) occurred in the group that received the higher dose.
机译：Rudgea viburnoides叶片被广泛用于流行的巴西医学中，作为利尿，抗风湿，降压和血液净化的茶。进行本研究以研究这种输注对Wistar大鼠肝脏和血浆生化参数的影响。两组在40天内每天接受10或20克干叶/升水的荚膜红景天叶输液。组织病理学分析未显示出变性区域或白细胞浸润。肝形态测定显示脂肪在治疗组的肝细胞中积累。血浆尿素，肌酐，尿酸，直接胆红素，胆固醇，总蛋白，白蛋白，γ-谷氨酰转移酶（γ-GT），丙氨酸转氨酶（ALT），天冬氨酸转氨酶（AST），氯，磷酸盐和钙。接受较高剂量的组中三酰甘油（TAG）的血浆水平显着降低。

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