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首页> 外文期刊>Cadernos de Saúde Pública >Use of antidepressants during breastfeeding: evaluating drug package inserts conformity with science-based bibliographical sourcesUso de medicamentos antidepresivos durante la lactancia: evaluación de la conformidad de los prospectos, respecto a fuentes b
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Use of antidepressants during breastfeeding: evaluating drug package inserts conformity with science-based bibliographical sourcesUso de medicamentos antidepresivos durante la lactancia: evaluación de la conformidad de los prospectos, respecto a fuentes b

机译:母乳喂养期间使用抗抑郁药:评估药品包装说明书是否与基于科学的书目来源相符母乳喂养期间使用抗抑郁药:评估包装说明书对来源的依从性b

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This article sought to evaluate the conformity between recommendations regarding antidepressant use during breastfeeding found in drug package inserts with recommendations from science-based bibliographic sources. We evaluated the standard drug package inserts of 23 antidepressants with active registration in Brazil. The presence of contraindications of antidepressant use during breastfeeding was compared with information present in the Brazilian Ministry of Health technical manual, the book Medications and Mothers’ Milk and on the databases LactMed, Micromedex and UpToDate. In most drug package inserts (62.5%), antidepressants are contraindicated during breastfeeding. Among bibliographical sources, that percentage varied between 0% and 25%. The study shows a low conformity between drug package inserts and bibliographical sources, alerting to the need for revising the content and presentation of information present in antidepressant drug package inserts in Brazil.
机译:本文旨在评估在药物包装说明书中发现的有关母乳喂养期间抗抑郁药使用的建议与来自科学文献目录的建议之间的一致性。我们评估了在巴西有效注册的23种抗抑郁药的标准药物包装插页。将母乳喂养期间使用抗抑郁药的禁忌症与巴西卫生部技术手册,《药物和母乳》一书以及数据库LactMed,Micromedex和UpToDate中的信息进行了比较。在大多数药物包装插页中(62.5%),母乳喂养期间禁忌使用抗抑郁药。在书目来源中,该百分比在0%到25%之间变化。该研究表明,药品包装说明书和书目来源之间的一致性较低,这提醒人们需要修改巴西抗抑郁药包装说明书中所含信息的内容和形式。

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