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首页> 外文期刊>Cadernos de Saúde Pública >Dengue and dengue hemorrhagic fever epidemics in Brazil: what research is needed based on trends, surveillance, and control experiences?
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Dengue and dengue hemorrhagic fever epidemics in Brazil: what research is needed based on trends, surveillance, and control experiences?

机译：巴西的登革热和登革出血热流行：根据趋势，监测和控制经验，需要进行哪些研究？

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摘要

Dengue epidemics account annually for several million cases and deaths worldwide. The high endemic level of dengue fever and its hemorrhagic form correlates to extensive domiciliary infestation by Aedes aegypti and multiple viral serotype human infection. This study analyzed serial case reports registered in Brazil since 1981, describing incidence evolutionary patterns and spatial distribution. Epidemic waves followed the introduction of every serotype (DEN 1 to 3), and reduction in susceptible individuals possibly accounted for decreasing case frequency. An incremental expansion of affected areas and increasing occurrence of dengue fever and its hemorrhagic form with high case fatality were noted in recent years. In contrast, efforts based solely on chemical vector control have been insufficient. Moreover, some evidence demonstrates that educational measures do not permanently modify population habits. Thus, as long as a vaccine is not available, further dengue control depends on potential results from basic interdisciplinary research and intervention evaluation studies, integrating environmental changes, community participation and education, epidemiological and virological surveillance, and strategic technological innovations aimed to stop transmission.
机译：登革热流行每年导致全球数百万例病例和死亡。登革热的高流行水平及其出血形式与埃及伊蚊广泛的定居点侵染和多种人血清型病毒感染有关。这项研究分析了自1981年以来在巴西注册的系列病例报告，描述了发病的演变模式和空间分布。伴随着每种血清型（DEN 1至3）的引入，流行病流行，易感人群的减少可能导致病例减少。近年来，人们注意到受灾地区的扩大扩大，登革热及其出血形式的增加以及高致死率。相反，仅基于化学载体控制的努力还不够。此外，一些证据表明，教育措施并不能永久改变人口习惯。因此，只要没有疫苗，进一步的登革热控制就取决于基础跨学科研究和干预评估研究的潜在结果，将环境变化，社区参与和教育，流行病学和病毒学监测以及旨在阻止传播的战略技术创新结合起来。

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