...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Cancer and Clinical Oncology >Nipple-Sparing Mastectomy via Inframammary Fold: Reconstructive Red Flags
【24h】

Nipple-Sparing Mastectomy via Inframammary Fold: Reconstructive Red Flags

机译：通过乳房下折叠保留乳头的乳房切除术：重建性红旗

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Background: Nipple-sparing mastectomy (NSM) is a technically feasible and oncologically sound option for patients who meet eligibility criteria. Inframammary fold (IMF) incision results in a well-hidden scar and enhanced final aesthetic result. While oncologic eligibility criteria have been well established, reconstructive criteria are less defined. We report Moffitt Cancer Center's (MCC) outcomes with IMF incision for NSM and immediate reconstruction, and factors associated with increased complication rate.Methods: IRB approved retrospective cohort study of patients who underwent NSM through an IMF approach with immediate reconstruction at MCC from 2006-2013 was conducted. Analysis included patient demographics, tumor characteristics, ancillary treatment, reconstructive method, and nipple and skin flap necrosis. A literature review was performed to compare outcomes with other types of incisions.Results: 115 patients met inclusion criteria, representing 199 breasts. The average age was 48.1 (range 18-74). The two main complication categories evaluated were nipple necrosis (8%) and skin flap necrosis (10.6%). Older age demonstrated a significant relationship with skin flap necrosis (p=0.0155) and overall complications (p=0.0492). Complication rate was significantly higher in the cancer side vs. prophylactic side in patients who underwent bilateral mastectomies (p=0.0088). Factors with trends related to increased skin flap necrosis included increased mastectomy specimen weight (p=0.0704), smoking (p=0.0726), and significant comorbidities (p=0.0665).Conclusion: Our institution's results substantiate that NSM through an IMF approach with immediate reconstruction is a viable option. Recognized risk factors such as age, laterality, breast weight, smoking history, and comorbidities associated with increased complications should be considered when determining patient selection for reconstruction.
机译：背景：对于符合资格标准的患者，保留乳头的乳房切除术（NSM）在技术上是可行的，在肿瘤学上也是合理的选择。乳房下褶皱（IMF）切口可导致隐匿的疤痕并增强最终的美学效果。虽然已经确定了肿瘤学资格标准，但对重建标准的定义较少。我们报告了Moffitt癌症中心（MCC）的IMF切口对NSM和即刻重建的预后以及与并发症发生率增加相关的因素。方法：IRB批准了一项回顾性队列研究，研究对象是从2006年以来通过IMF方法接受NSM并在MCC进行即刻重建的患者。 2013年进行了。分析包括患者的人口统计学，肿瘤特征，辅助治疗，重建方法以及乳头和皮瓣坏死。进行了文献综述以比较其他切口类型的结局。结果：115名患者符合入选标准，代表199例乳房。平均年龄为48.1（范围18-74）。评估的两个主要并发症类别是乳头坏死（8％）和皮瓣坏死（10.6％）。老年患者与皮瓣坏死（p = 0.0155）和总体并发症（p = 0.0492）有着显着关系。在接受双侧乳房切除术的患者中，癌症侧的并发症发生率明显高于预防侧（p = 0.0088）。与皮瓣坏死增加趋势相关的因素包括乳房切除术标本重量增加（p = 0.0704），吸烟（p = 0.0726）和严重合并症（p = 0.0665）。结论：我们机构的研究结果证实了NSM通过IMF方法立即采取行动重建是一个可行的选择。在确定重建患者的选择时，应考虑公认的危险因素，例如年龄，侧卧，乳房重量，吸烟史以及合并症与增加的并发症。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号