• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Canadian Journal of Pure and Applied Sciences >THE EFFECTIVENESS OF LEMON GRASS AND SAGE AQUEOUS EXTRACTS ON ACRYLAMIDE GENOTOXICITY
【24h】

THE EFFECTIVENESS OF LEMON GRASS AND SAGE AQUEOUS EXTRACTS ON ACRYLAMIDE GENOTOXICITY

机译：柠檬草和鼠尾草提取物对丙烯酰胺遗传毒性的影响。

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Acrylamide (ACR) is co mmonly used in biochemistry and biotechnology laboratories. It may also occur in our daily life; in deep - fried foods; baked goods; tap water and smoking which is also a major ACR producer. In this work, the ameliorative role of lemon grass and sage (1:1) aqueous extract against the toxic potential of acrylamide was investigated after 48 hours of simultaneo us treatm ents on albino rats. The 2, 2 - diphenyl - 1 - picrylhydrazyl assay was carried out to evaluate the antioxidant potential of the plant mixture which gave more activity than each plant alone; perhaps due to synergistic effect between the two plants . The result s o f acridine orange/ethidium bromide fluorescent staining and total genomic DN A electrophoresis of peripheral blood leukocytes revealed that high dose of plant mixture treatments has a significant amelioration against ACR toxicity. On the other hand , low dos e of plant mixture did not give that potential in micronucleus test of leukocytes, total genomic DNA electrophoresis of liver tissues and acridine orange/ethidium bro mide fluorescent staining of bone marrow tissues which indicated that low dose was better as ameliorative agent.
机译：丙烯酰胺（ACR）仅用于生物化学和生物技术实验室。它也可能发生在我们的日常生活中。在油炸食品中;焙烤食品;自来水和吸烟，这也是主要的ACR生产商。在这项工作中，对白化病大鼠同时治疗48小时后，研究了柠檬草和鼠尾草（1：1）水提取物对丙烯酰胺毒性潜力的改善作用。进行了2，2-二苯基-1-甲基苄基肼的试验，以评估该植物混合物的抗氧化能力，该混合物比单独的每种植物具有更高的活性。也许是由于两种植物之间的协同作用。 f啶橙/溴化乙锭荧光染色和总基因组DN A的电泳结果显示，外周血白细胞的高剂量处理显着改善了ACR毒性。另一方面，低剂量的植物混合物在白细胞微核试验，肝组织的全基因组DNA电泳和骨髓组织的cr啶橙/乙锭溴荧光染色方面没有这种潜力，表明低剂量的效果更好。改善剂。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号