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首页> 外文期刊>Cancer Imaging >Screening women at increased risk with MRI: Monday 3 October 2005, 08:45–10:45
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Screening women at increased risk with MRI: Monday 3 October 2005, 08:45–10:45

机译：使用MRI筛查风险较高的女性：2005年10月3日，星期一，08：45–10：45

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Breast cancer is the most common cancer affecting women. In the screening of women for breast cancer, mammography is the most used imaging modality. Women with an increased risk for getting breast cancer can develop a malignancy at a relatively young age compared to other women. The increased risk for developing breast cancer can usually be found in a positive familial history. This positive familial history is based on a gene mutation in 5–10% of cases. The most common gene mutations are BRCA1 and BRCA2. This risk makes it necessary to start screening these women at a young age. Mammography, however, has proven to be less reliable in younger women because its sensitivity is lowered due to the dense breast tissue often present in this group. MRI has a higher sensitivity for detecting breast cancer compared to mammography. MRI is not influenced by the density of the breast tissue. This makes breast MRI the best modality available for the screening of women with an increased risk for developing breast cancer.
机译：乳腺癌是影响女性的最常见癌症。在对女性乳腺癌的筛查中，乳腺X线摄影是最常用的成像方式。与其他女性相比，罹患乳腺癌风险增加的女性在相对年轻的年龄就可能发生恶性肿瘤。通常在阳性家族史中发现患乳腺癌的风险增加。这种阳性家族史是基于5-10％的病例中的基因突变。最常见的基因突变是BRCA 1 和BRCA 2 。这种风险使得有必要在年轻时开始筛查这些妇女。然而，由于年轻女性中经常存在致密的乳腺组织，因此乳房X线照相术在年轻女性中的可靠性较低，因为其敏感性降低。与乳腺摄影相比，MRI在检测乳腺癌方面具有更高的灵敏度。 MRI不受乳腺组织密度的影响。这使得乳房MRI成为筛查罹患乳腺癌风险增加的女性的最佳方法。

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