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首页> 外文期刊>Cancer Communications >Estimation of cancer burden in Guangdong Province, China in 2009
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Estimation of cancer burden in Guangdong Province, China in 2009

机译：2009年中国广东省的癌症负担估算

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Surveying regional cancer incidence and mortality provides significant data that can assist in making health policy for local areas; however, the province- and region-based cancer burden in China is seldom reported. In this study, we estimated cancer incidence and mortality in Guangdong Province, China and presented basic information for making policies related to health resource allocation and disease control. A log-linear model was used to calculate the sex-, age-, and registry-specific ratios of incidence to mortality (I/M) based on cancer registry data from Guangzhou, Zhongshan, and Sihui between 2004 and 2008. The cancer incidences in 2009 were then estimated according to representative I/M ratios and the mortality records from eight death surveillance sites in Guangdong Province. The cancer incidences in each city were estimated by the corresponding sex- and age-specific incidences from cancer registries or death surveillance sites in each area. Finally, the total and region-based cancer incidences and mortalities for the entire population of Guangdong Province were summarized. The estimated I/M ratios in Guangzhou (3.658), Zhongshan (2.153), and Sihui (1.527) were significantly different (P  0.001), with an average I/M ratio of 2.446. Significant differences in the estimated I/M ratios were observed between distinct age groups and the three cancer registries. The estimated I/M ratio in females was significantly higher than that in males (2.864 vs. 2.027, P  0.001). It was estimated that there were 163,376 new cancer cases (99,689 males and 63,687 females) in 2009; it was further estimated that 115,049 people (75,054 males and 39,995 females) died from cancer in Guangdong Province in 2009. The estimated crude and age-standardized rate of incidences (ASRI) in Guangdong Province were 231.34 and 246.87 per 100,000 males, respectively, and 156.98 and 163.57 per 100,000 females, respectively. The estimated crude and age-standardized rate of mortalities (ASRM) in Guangdong Province were 174.17 and 187.46 per 100,000 males, respectively, and 98.59 and 102.00 per 100,000 females, respectively. In comparison with the western area and the northern mountain area, higher ASRI and ASRM were recorded in the Pearl River Delta area and the eastern area in both males and females. Cancer imposes a heavy disease burden, and cancer patterns are unevenly distributed throughout Guangdong Province. More health resources should be allocated to cancer control, especially in the western and northern mountain areas.
机译：对区域癌症发病率和死亡率的调查提供了重要数据，可帮助制定当地卫生政策;但是，很少报道中国基于省和地区的癌症负担。在这项研究中，我们估算了中国广东省的癌症发病率和死亡率，并为制定有关卫生资源分配和疾病控制的政策提供了基本信息。基于2004年至2008年之间广州，中山和四会市的癌症登记数据，使用对数线性模型计算性别，年龄和登记信息特定的发病率与死亡率（I / M）的比率。癌症发生率然后根据代表性I / M比率和广东省8个死亡监测点的死亡率记录估算2009年的死亡率。每个城市的癌症发病率是根据每个地区的癌症登记处或死亡监测点的相应性别和年龄特定发病率来估算的。最后，总结了广东省全部人口的癌症总发病率和地区死亡率。广州（3.658），中山（2.153）和四会（1.527）的估计I / M比有显着差异（P <0.001），平均I / M比为2.446。在不同年龄组和三个癌症登记处之间观察到I / M比率的估计差异。女性的I / M估计值明显高于男性（2.864 vs. 2.027，P <0.001）。据估计，2009年有163,376例新癌症病例（男性99,689例，女性63,687例）。进一步估计，2009年广东省有115,049人死于癌症，其中男性为75,054人，女性为39,995人。广东省的估计粗略和年龄标准化发病率（ASRI）分别为100,000人为231.34和246.87。每10万名女性分别为156.98和163.57。广东省的估计死亡率和按年龄标准化的死亡率分别为每100,000男性174.17和187.46，以及每100,000女性98.59和102.00。与西部和北部山区相比，珠江三角洲地区和东部地区的男性和女性的ASRI和ASRM均较高。癌症给疾病带来了沉重的负担，而且癌症的分布在广东省各地分布不均。应该将更多的卫生资源用于癌症控制，尤其是在西部和北部山区。

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