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首页> 外文期刊>Canine Genetics and Epidemiology >Prevalence of pectinate ligament dysplasia and associations with age, sex and intraocular pressure in the Basset hound, Flatcoated retriever and Dandie Dinmont terrier
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Prevalence of pectinate ligament dysplasia and associations with age, sex and intraocular pressure in the Basset hound, Flatcoated retriever and Dandie Dinmont terrier

机译：巴塞特猎犬，Flatcoated猎犬和Dandie Dinmont梗中果胶韧带发育不良的发生率及其与年龄，性别和眼压的关系

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BackgroundThe aims of this study were to: determine the prevalence of pectinate ligament dysplasia (PLD) in populations of Basset hounds (BH), Flatcoated retrievers (FCR) and Dandie Dinmont terriers (DDT) resident in the UK; investigate possible associations between the degree of PLD and age, sex and intraocular pressure (IOP) and; investigate possible associations between IOP and age and sex. Gonioscopy was performed in both eyes of 198 BH, 170 FCR and 95 DDT and the percentage of iridocorneal angle affected by PLD was estimated and classified as unaffected (0?%), mildly affected (90?%). Rebound tonometry was performed bilaterally in the majority of enrolled dogs. ResultsSeventy-six of 198 (38.4?%) BH, 36/170 (21.2?%) FCR and 21/95 (22.1?%) DDT were moderately or severely affected by PLD. The prevalence of PLD was significantly higher in BH than both FCR and DDT. In all breeds there was a significant positive correlation between PLD and age. In the BH only there was a significant association between PLD and sex. In the DDT only there was a weak negative correlation between PLD and IOP and a moderately strong negative correlation between IOP and age. ConclusionsPLD is prevalent and significantly associated with age in all three breeds we investigated. The linear relationship between PLD and age can be explained by the progression of PLD over time which would contribute to the high prevalence of PLD despite widespread screening.
机译：背景本研究的目的是：确定居住在英国的巴塞特猎犬（BH），扁平猎犬（FCR）和丹迪·丁蒙特梗（DDT）人群中的果胶韧带发育不良（PLD）的患病率;研究PLD程度与年龄，性别和眼压（IOP）之间的可能关联;以及调查眼压与年龄和性别之间的可能联系。在198 BH，170 FCR和95 DDT的两只眼睛中进行了角膜镜检查，并估计了受PLD影响的虹膜角膜百分比，并将其分为未受影响（0％），轻度受影响（90％）。在大多数已登记的狗中，双侧进行回弹眼压测定。结果198（38.4％）的BH，36/170（21.2％）的FCR和21/95（22.1％）的DDT受PLD的中度或严重影响。 BH中PLD的患病率明显高于FCR和DDT。在所有品种中，PLD与年龄之间存在显着的正相关。在BH中，只有PLD与性别之间存在显着关联。在滴滴涕中，只有PLD与IOP之间存在弱的负相关，而IOP与年龄之间存在中等的负相关。结论在我们调查的所有三个品种中，PLD普遍存在并且与年龄显着相关。 PLD与年龄之间的线性关系可以通过PLD随时间的进展进行解释，尽管进行了广泛的筛查，这仍将有助于PLD的高流行。

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