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首页> 外文期刊>Cardiology Research >Clinical and Surgical Strategies for Avoiding or Reducing Allogeneic Blood Transfusions
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Clinical and Surgical Strategies for Avoiding or Reducing Allogeneic Blood Transfusions

机译：避免或减少异体输血的临床和手术策略

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Blood transfusions have still been used as a standard therapy to treat severe anemia. Current evidences point to both excessive allogeneic blood consumption and decreased donations, which result in reduced stocks in blood banks. Several studies have increasingly suggested a more restrictive transfusion practice for blood products. Currently, a number of autologous blood conservation protocols in surgeries have been noted. We report a case of severe anemia with 2.9 g/dL hemoglobin, which was successfully handled without using the standard therapy to treat anemia with hemotransfusions. Such a case of severe anemia condition resulted after the patient was submitted to ascending aortic aneurism repair, valvar aortic replacement, reimplantation of right coronary ostium, followed by a coronary artery bypass grafting and several postoperative complications. The main clinical and surgical strategies used in this case to avoid blood transfusions were acute normovolemic hemodilution, intraoperative blood cell salvage, and meticulous hemostasis, beyond epsilon-aminocaproic acid, desmopressin, prothrombin complex concentrate, human fibrinogen concentrate, factor VIIa recombinant, erythropoietin and hyperoxic ventilation.Cardiol Res. 2016;7(2):84-88doi: http://dx.doi.org/10.14740/cr463w
机译：输血仍被用作治疗严重贫血的标准疗法。当前的证据表明，同种异体的血液消耗过多，而捐赠却减少了，这导致了血库的减少。越来越多的研究提出对血液制品的限制性输血实践。当前，已经注意到外科手术中的许多自体血液保存方案。我们报告了2.9 g / dL血红蛋白引起的严重贫血，无需使用标准疗法通过输血治疗贫血即可成功治疗。在患者接受升主动脉瘤修复，瓣膜主动脉置换，右冠状动脉造口再植入，冠状动脉搭桥术和一些术后并发症之后，出现了这种严重贫血的情况。在这种情况下，避免输血的主要临床和外科策略是急性降血常规血液稀释，术中挽救血液和细致止血，除了ε-氨基己酸，去氨加压素，凝血酶原复合物浓缩物，人纤维蛋白原浓缩物，VIIa重组因子，促红细胞生成素和高氧通气。 2016; 7（2）：84-88doi：http://dx.doi.org/10.14740/cr463w

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