Successful Treatment of an Infant with Left Ventricular Noncompaction Presenting with Fatal Ventricular Arrhythmia Treated with Cardiac Resynchronization Therapy and an Implantable Cardioverter Defibrillator

Masato Kimura; Kengo Kawano; Hisao Yaoita; Shigeo Kure

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Successful Treatment of an Infant with Left Ventricular Noncompaction Presenting with Fatal Ventricular Arrhythmia Treated with Cardiac Resynchronization Therapy and an Implantable Cardioverter Defibrillator

机译：心脏再同步治疗和植入式心脏复律除颤器治疗致命性室性心律失常伴左室不紧致婴儿的成功治疗

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We herein report the successful treatment of a 4-year-old girl with left ventricular noncompaction (LVNC) who presented with incessant ventricular fibrillation at 5 months of age. An implantable cardioverter defibrillator (ICD) was implanted, and dual chamber (DDD) pacing was initiated at 7 months of age. At her 10-month follow-up, her left ventricular ejection fraction (LVEF) had decreased from 45% to 20% with mechanical dyssynchrony. After upgrading to cardiac resynchronization therapy (CRT), the LVEF improved to 50%. The usefulness of CRT in pediatric LVNC has not been fully elucidated. However, our case suggests that CRT therapy may be an effective option for LVNC-induced cardiac dysfunction.

机译：我们在这里报告成功治疗一名4岁左心功能不全（LVNC）的女孩，该女孩在5个月大时出现持续性心室颤动。植入可植入式心脏复律除颤器（ICD），并在7个月大时开始双腔起搏（DDD）起搏。在她的10个月随访中，由于机械不同步，她的左心室射血分数（LVEF）从45％降低到20％。升级为心脏再同步治疗（CRT）后，LVEF提高到50％。 CRT在儿科LVNC中的用途尚未完全阐明。但是，我们的案例表明，CRT治疗可能是LVNC诱发的心脏功能障碍的有效选择。

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《Case Reports in Cardiology》 |2018年第2011期|共页
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Masato Kimura; Kengo Kawano; Hisao Yaoita; Shigeo Kure;
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1. Association left ventricular lead and ventricular arrhythmias after upgrade to cardiac resynchronization therapy in patients with implantable cardioverter defibrillators [J] . Mitsuharu Kawamura, Shuhei Arai, Kosuke Yoshikawa, Clinical cardiology. . 2019,第7期

机译：植入式心脏复律除颤器患者升级为心脏再同步治疗后左心室铅与心律失常的关联
2. Left Ventricular Ejection Fraction Normalization in Cardiac Resynchronization Therapy and Risk of Ventricular Arrhythmias and Clinical Outcomes Results From the Multicenter Automatic Defibrillator Implantation Trial With Cardiac Resynchronization Therapy (MADIT-CRT) Trial [J] . Ruwald Martin H., Solomon Scott D., Foster Elyse, Circulation: An Official Journal of the American Heart Association . 2014,第25期

机译：心脏再同步治疗中的左心室射血分数归一化和室性心律失常的风险以及临床结果来自于采用心脏再同步治疗（MADIT-CRT）的多中心自动除颤器植入试验
3. Implantable cardioverter-defibrillator and cardiac resynchronization therapy in patients with left ventricular noncompaction. [J] . Kobza R, Steffel J, Erne P, Heart rhythm: the official journal of the Heart Rhythm Society . 2010,第11期

机译：植入式心脏复律除颤器和心脏再同步治疗左心室不紧致患者。
4. Development of an algorithm for detection of fatal cardiac arrhythmia for implantable cardioverter-defibrillator using a self-organizing map [C] . Hiroyuki Kinoshita, Makoto Yoshizawa, Masashi Inagaki, . 2006

机译：利用自组织图检测植入式心脏复律除颤器致命性心律失常的算法
5. Electromechanical Wave Imaging in the Clinic: Localization of Atrial and Ventricular Arrhythmias and Quantification of Cardiac Resynchronization Therapy Response [D] . ?Melki, Lea 2020

机译：临床中的机电波成像：心房和心间心律失常的定位和心脏重新同步治疗反应的定量
6. Successful Treatment of an Infant with Left Ventricular Noncompaction Presenting with Fatal Ventricular Arrhythmia Treated with Cardiac Resynchronization Therapy and an Implantable Cardioverter Defibrillator [O] . Masato Kimura, Kengo Kawano, Hisao Yaoita, 2018

机译：心脏再同步治疗和植入式心脏复律除颤器治疗致命性室性心律失常伴左室不紧致婴儿的成功治疗
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机译：左心室收缩功能障碍的心脏再同步治疗和植入式心脏除颤器。证据报告/技术评估编号152

Successful Treatment of an Infant with Left Ventricular Noncompaction Presenting with Fatal Ventricular Arrhythmia Treated with Cardiac Resynchronization Therapy and an Implantable Cardioverter Defibrillator

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