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Apoptotic membrane dynamics in health and disease

机译:健康和疾病中的细胞凋亡膜动力学

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Abstract: Apoptosis, also known as programmed cell death, is a fundamental homeostatic mechanism essential for normal embryonic development and the maintenance of healthy adult tissues. The processes that affect cell membrane dynamics during the tightly regulated apoptotic program have attracted considerable interest over the years. Distinct biochemical and structural alterations to plasma membrane composition and topography contribute to the efficient removal of cellular corpses. In this review, we will discuss these membrane alterations and their importance in maintaining cell and tissue homeostasis.
机译:摘要:细胞凋亡,也称为程序性细胞死亡,是基本的稳态机制,对正常的胚胎发育和健康的成人组织的维持至关重要。这些年来,在严格调控的凋亡程序中影响细胞膜动力学的过程引起了人们的极大兴趣。质膜组成和形貌的明显生化和结构改变有助于有效去除细胞尸体。在这篇综述中,我们将讨论这些膜改变及其在维持细胞和组织动态平衡中的重要性。

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