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首页> 外文期刊>Cardiovascular Ultrasound >Comparison of mitral annulus geometry between patients with ischemic and non-ischemic functional mitral regurgitation: implications for transcatheter mitral valve implantation
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Comparison of mitral annulus geometry between patients with ischemic and non-ischemic functional mitral regurgitation: implications for transcatheter mitral valve implantation

机译：缺血性和非缺血性二尖瓣反流患者二尖瓣环几何形状的比较：经导管二尖瓣植入术的意义

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Transcatheter mitral valve replacement (TMVR) is a new therapeutic option for high surgical risk patients with mitral regurgitation (MR). Mitral valve (MV) geometry quantification is of paramount importance for success of the procedure and transthoracic 3D echocardiography represents a useful screening tool. Accordingly, we sought to asses MV geometry in patients with functional MR (FMR) that would potentially benefit of TMVR, focusing on the comparison of mitral annulus (MA) geometry between patients with ischemic (IMR) and non ischemic mitral regurgitation (nIMR). We retrospectively selected 94 patients with severe FMR: 41 (43,6%) with IMR and 53 (56,4%) with nIMR. 3D MA analysis was performed on dedicated transthoracic 3D data sets using a new, commercially-available software package in two moments of the cardiac cycle (early-diastole and mid-systole). We measured MA dimension and geometry parameters, left atrial and left ventricular volumes. Maximum (MA area 10.7?±?2.5?cm2 vs 11.6?±?2.7?cm2, p??0.05) and the best fit plane MA area (9.9?±?2.3?cm2 vs 10.7?±?2.5?cm2, p??0.05, respectively) were similar between IMR and nIMR. nIMR patients showed larger mid-systolic 3D area (9.8?±?2.3?cm2 vs 10.8?±?2.7?cm2, p 0.05). Patients with ischemic and non-ischemic etiology of FMR have similar maximum dimension, yet systolic differences between the two groups should be taken into account to tailor prosthesis’s selection. N.A.
机译：经导管二尖瓣置换术（TMVR）是具有高手术风险的二尖瓣反流（MR）患者的新治疗选择。二尖瓣（MV）几何量化对于手术成功与否至关重要，经胸3D超声心动图是一种有用的筛查工具。因此，我们试图评估可能有益于TMVR的功能性MR（FMR）患者的MV几何形状，重点是比较缺血性（IMR）和非缺血性二尖瓣关闭不全（nIMR）患者的二尖瓣环（MA）几何形状。我们回顾性选择了94例严重FMR患者：41例（43.6％）IMR和53例（56.4％）nIMR。在心动周期的两个瞬间（舒张早期和收缩中期），使用新型的，可商购的软件包对专用的经胸3D数据集进行3D MA分析。我们测量了MA的尺寸和几何参数，左心房和左心室容积。最大（MA面积10.7？±？2.5？cm2与11.6？±？2.7？cm2，p？>？0.05）和最佳拟合平面MA面积（9.9？±？2.3？cm2对10.7？±？2.5？cm2， IMR和nIMR之间的p？>？0.05分别相似。 nIMR患者的收缩中3D面积更大（9.8？±？2.3？cm2与10.8？±？2.7？cm2，p 0.05）。患有FMR缺血性和非缺血性病因的患者具有相似的最大尺寸，但应考虑两组之间的收缩期差异以适应假体的选择。不适用

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