...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Cardiovascular Ultrasound >Assessment of left ventricular systolic and diastolic abnormalities in patients with hypertrophic cardiomyopathy using real-time three-dimensional echocardiography and two-dimensional speckle tracking imaging
【24h】

Assessment of left ventricular systolic and diastolic abnormalities in patients with hypertrophic cardiomyopathy using real-time three-dimensional echocardiography and two-dimensional speckle tracking imaging

机译：实时三维超声心动图和二维斑点追踪成像评估肥厚型心肌病患者左室收缩和舒张异常

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Conventional echocardiography is not sensitive enough to assess left ventricular (LV) dysfunction in hypertrophic cardiomyopathy (HCM) patients. This research attempts to find a new ultrasonic technology to better assess LV diastolic function, systolic function, and myocardial longitudinal and circumferential systolic strain of segments with different thicknesses in HCM patients. This study included 50 patients with HCM and 40 healthy subjects as controls. The peak early and late mitral annulus diastolic velocities at six loci (Ea′ and Aa′, respectively) and the Ea′/Aa′ ratio were measured using real-time tri-plane echocardiography and quantitative tissue velocity imaging (RT-3PE-QTVI). The mean value of Ea′ at six loci (Em′) was obtained for the calculation of E/Em′ ratio. The LV end-diastolic volume (LVEDV), LV end-systolic volume (LVESV), LV stroke volume (LVSV), and LV ejection fraction (LVEF) were measured using real-time three-dimensional echocardiography (RT-3DE). LV myocardial longitudinal peak systolic strain (LPSS) and circumferential peak systolic strain (CPSS) in the apical-middle-basal segments (LPSS-api, LPSS-mid, LPSS-bas; CPSS-api, CPSS-mid, and CPSS-bas, respectively) were obtained using a software for two-dimensional speckle tracking imaging (2D-STI). According to the different segmental thicknesses (STs) in each HCM patient, the values (LPSS and CPSS) of all the myocardial segments were categorized into three groups and the respective averages were computed. The Ea′, Aa′, and, Ea′/Aa’ ratio in HCM patients were lower than those in the controls (all p??0.001), while the E/Em′ ratio in HCM patients was higher than that in the controls (p??0.001). The LVEDV, LVSV, and LVEF were significantly lower in HCM patients than in controls (all p??0.001). In HCM patients, the LPSS-api, LPSS-mid, LPSS-bas, CPSS-api, CPSS-mid, and CPSS-bas and the LPSS and CPSS of LV segments with different thicknesses were all significantly reduced (all p??0.001). In HCM patients, myocardial dysfunction was widespread not only in the obviously hypertrophic segments but also in the non-hypertrophic segments; the LV systolic and diastolic functions were damaged, even with a normal LVEF. LV diastolic dysfunction, systolic dysfunction, and myocardial deformation impairment in HCM patients can be sensitively revealed by RT-3PE-QTVI, RT-3DE, and 2D-STI.
机译：常规超声心动图检查不足以评估肥厚型心肌病（HCM）患者的左心室（LV）功能障碍。本研究试图找到一种新的超声技术，以更好地评估HCM患者不同厚度的节段的LV舒张功能，收缩功能以及心肌纵向和周向收缩应变。这项研究纳入了50例HCM患者和40例健康受试者作为对照。使用实时三平面超声心动图和定量组织速度成像（RT-3PE-QTVI）测量六个位点（分别为Ea'和Aa'）的二尖瓣环舒张早期和晚期峰值速度以及Ea'/ Aa'比）。计算六个位点（Em'）的Ea'平均值，以计算E / Em'比。使用实时三维超声心动图（RT-3DE）测量左室舒张末期容积（LVEDV），左室收缩末期容积（LVESV），左室卒中容积（LVSV）和左室射血分数（LVEF）。心尖-中-基底节段（LPSS-api，LPSS-mid，LPSS-bas，CPSS-api，CPSS-mid和CPSS-bas）的LV心肌纵向峰值收缩压应变（LPSS）和圆周峰值收缩压应变（CPSS） ，分别使用二维斑点跟踪成像（2D-STI）软件获得。根据每个HCM患者的不同节段厚度（STs），将所有心肌节段的值（LPSS和CPSS）分为三组，并计算各自的平均值。 HCM患者的Ea'，Aa'和Ea'/ Aa'比值均低于对照组（均p 0.001），而HCM患者的E / Em'比值高于对照组。对照（p≤0.001）。 HCM患者的LVEDV，LVSV和LVEF显着低于对照组（所有p <0.001）。在HCM患者中，不同厚度的LV段的LPSS-api，LPSS-mid，LPSS-bas，CPSS-api，CPSS-mid和CPSS-bas以及LPSS和CPSS均显着降低（所有p？<？ 0.001）。在HCM患者中，心肌功能障碍不仅在明显的肥大区域中普遍存在，而且在非肥大区域中也很普遍。即使LVEF正常，LV的收缩和舒张功能也会受损。 RT-3PE-QTVI，RT-3DE和2D-STI可以敏感地揭示HCM患者的左室舒张功能障碍，收缩功能障碍和心肌变形障碍。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号