...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Cellular Physiology and Biochemistry >Superimposition of an Incoherent Magnetic Field Eliminated the Inhibition of Hormone Secretion Induced by a 50-Hz Magnetic Field in Human Villous Trophoblasts in vitro
【24h】

Superimposition of an Incoherent Magnetic Field Eliminated the Inhibition of Hormone Secretion Induced by a 50-Hz Magnetic Field in Human Villous Trophoblasts in vitro

机译：非相干磁场的叠加消除了人绒毛滋养细胞体外50 Hz磁场诱导的激素分泌的抑制作用。

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The effects of exposure to a sinusoidal 50-Hz magnetic field (MF) and an incoherent (noise) MF on hormone secretion in human first trimester villous trophoblasts were investigated. Trophoblasts were isolated from more than 30 first trimester human chorionic villi of 8-10 weeks gestation. They were cultured and exposed to MFs for different durations. The concentrations of human chorionic gonadotropin (hCG) and progesterone in culture medium were measured by electrochemiluminescence immunoassay. The results showed that exposure of the villous trophoblasts to a 50-Hz MF at 0.4 mT (milli Tesla) for 72 hrs could significantly inhibit the secretion of hCG and progesterone, whereas exposure to an incoherent MF (frequency range between 30 to 90 Hz) with the same conditions did not significantly affect the secretion. However, when the incoherent MF was superimposed on the 50-Hz MF and the cells were exposed to both fields simultaneously, no significant change in hormone secretion was observed. Based on these results, we concluded that 50-Hz MF exposure for 72 hrs could inhibit the hormone secretion of trophoblasts, and an incoherent MF of equal intensity could completely eliminate the effects induced by the 50-Hz MF.
机译：研究了暴露于正弦50 Hz磁场（MF）和不连贯（噪声）MF对人早孕绒毛滋养层细胞激素分泌的影响。从妊娠8-10周的30多个孕早期绒毛膜绒毛中分离出滋养细胞。将它们培养并暴露于MF不同的持续时间。通过电化学发光免疫测定法测量培养基中人绒毛膜促性腺激素（hCG）和孕酮的浓度。结果表明，将绒毛滋养层细胞暴露于0.4 mT（milli Tesla）的50 Hz MF持续72小时可以显着抑制hCG和孕酮的分泌，而暴露于不连贯的MF（频率范围为30至90 Hz）在相同条件下并没有明显影响分泌。但是，当非相干MF叠加在50 Hz MF上并且细胞同时暴露于两个电场时，未观察到激素分泌的显着变化。根据这些结果，我们得出结论，50 Hz MF暴​​露72小时可以抑制滋养细胞的激素分泌，而等强度的非相干MF则可以完全消除50 Hz MF引起的影响。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号