MiR-141 Activates Nrf2-Dependent Antioxidant Pathway via Down-Regulating the Expression of Keap1 Conferring the Resistance of Hepatocellular Carcinoma Cells to 5-Fluorouracil

Liang Shi; Lili Wu; Zhanguo Chen; Jianrong Yang; Xiaofei Chen; Fangyou Yu; Fang Zheng; Xiangyang Lin

首页> 外文期刊>Cellular Physiology and Biochemistry >MiR-141 Activates Nrf2-Dependent Antioxidant Pathway via Down-Regulating the Expression of Keap1 Conferring the Resistance of Hepatocellular Carcinoma Cells to 5-Fluorouracil

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MiR-141 Activates Nrf2-Dependent Antioxidant Pathway via Down-Regulating the Expression of Keap1 Conferring the Resistance of Hepatocellular Carcinoma Cells to 5-Fluorouracil

机译：MiR-141通过下调Keap1的表达赋予肝细胞癌细胞对5-氟尿嘧啶的抗性，从而激活Nrf2依赖性抗氧化剂途径。

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《Cellular Physiology and Biochemistry》 |2015年第6期|共16页
作者
Liang Shi; Lili Wu; Zhanguo Chen; Jianrong Yang; Xiaofei Chen; Fangyou Yu; Fang Zheng; Xiangyang Lin;
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中图分类细胞生物物理学;
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1. Succination of Keap1 and activation of Nrf2-dependent antioxidant pathways in FH-deficient papillary renal cell carcinoma type 2. [J] . Kinch L, Grishin NV, Brugarolas J Cancer Cell . 2011,第4期

机译：Keap1的琥珀酸化和Nrf2依赖的抗氧化途径在FH缺陷型2型乳头状肾细胞癌中的激活。
2. miR-340 Reverses Cisplatin Resistance of Hepatocellular Carcinoma Cell Lines by Targeting Nrf2-dependent Antioxidant Pathway [J] . Liang Shi, Zhan-Guo Chen, Li-li Wu, Asian Pacific Journal of Cancer Prevention . 2015,第23期

机译：miR-340通过靶向NRF2依赖性抗氧化途径反转肝细胞癌细胞系的顺铂抗性
3. lncRNA KRAL reverses 5-fluorouracil resistance in hepatocellular carcinoma cells by acting as a ceRNA against miR-141 [J] . Lili Wu, Chenwei Pan, Xin Wei, Cell Communication and Signaling . 2018,第1期

机译：lncRNA KRAL通过充当针对miR-141的ceRNA逆转肝癌细胞中的5-氟尿嘧啶耐药性
4. The Role of the PI3K Pathway in Anti-IgM (Anti-i) - ensitive and -Resistant B-cell Lymphomas Failure to Disengage PI3K Pathway Signaling Confers i-fi Resistance on the CH12 B Cell Lymphoma [C] . Gregory B. Carey, Laura Tonnetti, David W. Scott International Symposium on Programmed Cell Death . 2003

机译：PI3K途径在抗IgM（抗IgM（抗-Ig）的作用 - 最终和 - 抗生素B细胞淋巴瘤未脱离PI3K途径信号传导对CH12 B细胞淋巴瘤的I-FI阻力
5. Mechanistic Study of the Effect of CDH1 Promoter Hypermethylation on Drug Resistance and Related Gene Expression in Multidrug Resistant Human Hepatocellular Carcinoma R-HepG2 Cells. [D] . Jiang, Lei. 2010

机译：CDH1启动子甲基化对多药耐药人肝细胞癌R-HepG2细胞耐药性及相关基因表达影响的机理研究。
6. Succination of Keap1 and activation of Nrf2-dependent antioxidant pathways in FH-deficient papillary renal cell carcinoma type-2 [O] . Lisa Kinch, Nick V. Grishin, James Brugarolas -1

机译：Keap1的丁二酸和FH-缺陷乳头状肾细胞癌类型2的Nrf2依赖性抗氧化剂途径的激活
7. MiR-141 Activates Nrf2-Dependent Antioxidant Pathway via Down-Regulating the Expression of Keap1 Conferring the Resistance of Hepatocellular Carcinoma Cells to 5-Fluorouracil [O] . Liang Shi, Lili Wu, Zhanguo Chen, 2015

机译：miR-141通过下调Keap1的表达激活Nrf2依赖性抗氧化途径，使肝细胞癌细胞对5-氟尿嘧啶具有抗性

MiR-141 Activates Nrf2-Dependent Antioxidant Pathway via Down-Regulating the Expression of Keap1 Conferring the Resistance of Hepatocellular Carcinoma Cells to 5-Fluorouracil

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