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首页> 外文期刊>Ceylon Medical Journal >Fetal Doppler reference values in women with a normal body mass index
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Fetal Doppler reference values in women with a normal body mass index

机译：体重指数正常的女性的胎儿多普勒参考值

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ObjectivesTo construct gestation specific reference limits for fetal umbilical (UA), middle cerebral artery (MCA) pulsatility indices (PI) and the cerebroplacental ratio (CPR) in singleton pregnancies with normal BMI between 16 and 40 weeks of gestation.MethodsWe ultrasonographically examined 596 fetuses from women with normal nutritional and health status and minimal environmental constraints on fetal growth. Each mother was considered only once for measurement of fetal Doppler indices, at gestations between 16 and 40 weeks in a prospective cross-sectional study. Gestational age was confirmed by fetal crown-rump length measurement between 11 and 14 weeks. Pulsatility indices of umbilical and middle cerebral arteries were measured by real time and Doppler ultrasonography. CPR ratio was calculated by dividing MCA PI by UA PI. The fetal Doppler measurements obtained from the current study were compared with commonly used reference charts. For each parameter separate polynomial regression models were fitted to estimate the gestation specific means and standard deviations, assuming that the measurements have a normal distribution at each gestational age.ResultsA significant difference of fetal Doppler indices was observed between our study and previously published reference charts for most gestational weeks. The fitted 10th, 50th and 90th centiles at 40 weeks of gestation were 0.65, 0.87 and 1.08 for UA PI; 0.93, 1.32 and 1.71 MCA PI; 1.02, 1.58 and 2.13 for CPR.ConclusionsThese charts can be used for better defining the normal range of fetal arterial Doppler indices. This will be useful in the diagnosis and management of fetuses with abnormal fetal growth.
机译：目的建立妊娠期16至40周的BMI正常的单胎妊娠的胎儿脐血（UA），大脑中动脉（MCA）搏动指数（PI）和脑胎盘比（CPR）的妊娠特异性参考限。方法我们超声检查了596例胎儿营养和健康状况正常且对胎儿生长影响最小的女性。在一项前瞻性横断面研究中，每个母亲在妊娠16至40周时仅被考虑一次用于测量胎儿多普勒指数。通过测量胎冠臀长在11至14周之间可以确认妊娠年龄。通过实时和多普勒超声测量脐带和中脑动脉搏动指数。通过将MCA PI除以UA PI来计算CPR比。从当前研究获得的胎儿多普勒测量值与常用参考图进行比较。对于每个参数，假设测量值在每个胎龄时均呈正态分布，则拟合单独的多项式回归模型以估计胎龄特定平均值和标准差。结果在我们的研究与先前发表的参考图之间发现胎儿多普勒指数存在显着差异大多数孕周。 UA PI在妊娠40周时拟合的第10、50和90％分别为0.65、0.87和1.08。 0.93、1.32和1.71 MCA PI; CPR的1.02、1.58和2.13结论这些图表可用于更好地定义胎儿多普勒指数的正常范围。这对于胎儿发育异常的胎儿的诊断和治疗很有用。

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